2014 Grant Recipients

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MIRI Team Grants

Adolescent mental health
Principal Investigator: Jean Addington, University of Calgary
AMOUNT: $1,387,285.40

Biomarkers for crossing the translational divide in acute spinal cord injury
Principal Investigator: Brian Kwon, University of British Columbia
AMOUNT: $2,775,000.00

Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial
Principal Investigator: Zafiris Daskalakis, Centre for Addiction and Mental Health
AMOUNT: $1,387,500.00

Distinct neuro-immune interactions drive sex differences in chronic pain
Principal Investigator: Jeffrey Mogil, McGill University
AMOUNT: $2,294,000.00

Modulating memory circuits: focal DBS treatments to improve medial temporal lobe function
Principal Investigator: Kari Hoffman, York University
AMOUNT: $1,387,294.65

Neurobiological correlates of TMS
Principal Investigator: Doris Doudet, University of British Columbia
AMOUNT: $865,517.00

Stimulating endogenous regeneration of photoreceptors as a potential cure for blindness
Principal Investigator: Rod Bremner, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
AMOUNT: $1,387,869.08

Targeting the synaptic pathway in neurodevelopmental and psychiatric disorders
Principal Investigator: Ann Marie Craig, Brain Research Centre, University of British Columbia
AMOUNT: $1,387,500.00

The Frontier Trial - Field Randomization of NA-1 Treatment In Early Responders
Principal Investigator: Laurie Morrison, University of Toronto
AMOUNT: $6,068,833.00

Understanding stress to improve mental health
Principal Investigator: Jaideep Bains, University of Calgary
AMOUNT: $1,387,500.00


British Columbia Alzheimer’s Research Award Program

Locally produced brain insulin in memory and Alzheimer’s disease: A multidisciplinary approach to a key question
Principal Investigator: James Johnson, University of British Columbia
AMOUNT: $987,000.00

Novel retinal biomarkers for Alzheimer’s disease
Principal Investigator: Mirza Faisal Beg, Simon Fraser University
AMOUNT: $1,406,835.90

Preclincal development of a disease modifying small molecule therapy for Alzheimer disease
Principal Investigator: David Vocadlo, Simon Fraser University
AMOUNT: $1,410,000.00

Targeting amyloid propagation in Alzheimer disease: structures, immunology and extracellular vesicle topology
Principal Investigator: Neil Cashman, University of British Columbia
AMOUNT: $1,406,191.10

Validation of Connexins and Pannexins as a target for Alzheimer’s Disease
Principal Investigator: Christian Naus, University of British Columbia
AMOUNT: $1,410,000.00


Platform Support Grants

A National biobank and database for patients with traumatic brain injury
Principal Investigator: Jamie Hutchison, The Hospital for Sick Children
AMOUNT: $2,775,000.00

A Novel Zebrafish-Based Platform for Anticonvulsant Drug Development
Principal Investigator: Deborah Kurrasch, University of Calgary
AMOUNT: $2,731,867.25

A research platform to study animal and human cellular models of neurological disorders
Principal Investigator: Karun Singh, McMaster University
AMOUNT: $277,500.00

Building the Rick Hansen Alberta Spinal Cord Injury Registry
Principal Investigator: Chester Ho, University of Calgary
AMOUNT: $832,394.55

CBRAIN: Canadian Brain Research and Informatics Platform
Principal Investigator: Alan Evans, McGill University
AMOUNT: $2,775,000.00

Douglas-Bell Canada Brain Bank, an essential platform for brain research in Canada
Principal Investigator: Gustavo Turecki, Douglas Hospital Research Centre
AMOUNT: $1,883,300.00

Human inducible pluripotent stem cells (iPSC) platform
Principal Investigator: Jack Puymirat, Université Laval
AMOUNT: $1,526,250.00

Integrated Neurostimulation Platform for Neuropsychiatric Research
Principal Investigator: Fidel Vila-Rodriguez, University of British Columbia
AMOUNT: $277,500.00

Manitoba Neuroimaging Platform
Principal Investigator: Christopher Anderson, University of Manitoba
AMOUNT: $277,500.00

Montreal functional brain imaging platform
Principal Investigator: Amir Shmuel, McGill University
AMOUNT: $277,500.00

Quebec Neuroscience and Mental Health Imaging Consortium: The regional leader in human neuroimaging
Principal Investigator: Pascale Tremblay, Institut Universitaire en Santé Mentale de Québec

Regeneration Unit in Neurology: A platform for research and training in advanced microscopy and behavioural approaches
Principal Investigator: Patrick Whelan, University of Calgary
AMOUNT: $277,500.00

The Canadian Neonatal Brain Platform
Principal Investigator: Gregory Lodygensky, Sainte-Justine University Hospital Research Centre
AMOUNT: $2,564,100.00

The Canadian Neurophotonics Platform
Principal Investigator: Yves De Koninck, Université Laval
AMOUNT: $6,105,000.00

The Experimental Imaging Centre: a Local Brain Canada Platform for Preclinical MR Neuroimaging
Principal Investigator: Jeff Dunn, University of Calgary
AMOUNT: $277,500.00

The Ontario Brain Epigenomics Platfrom
Principal Investigator: Art Petronis, Centre for Addiction and Mental Health
AMOUNT: $832,500.00

Z-BRAIN: A Zebrafish Drug Screening Platform Targeting Brain Disorders
Principal Investigator: Xiao-Yan Wen, St. Michael’s Hospital
AMOUNT: $2,423,500.00


ALS Canada - Brain Canada Discovery Grants

Characterizing the C9ORF72 protein interactome for identifying novel pathogenic pathways in ALS
Principal Investigator: Janice Robertson, University of Toronto
AMOUNT: $100,000.00

Epigenetic mechanisms underlying dendritic atrophy in ALS
Principal Investigator: Heather Durham, McGill University, Montreal Neurological Institute and Hospital
AMOUNT: $100,000.00

Investigation of the innate immune system and motor neuron degeneration in genetic models of ALS
Principal Investigator: Alex Parker, Université de Montréal
AMOUNT: $100,000.00

Synaptic inhibition in the motor cortex of an ALS mouse model
Principal Investigator: Melanie Woodin, University of Toronto
AMOUNT: $100,000.00

Use of bone marrow cells to deliver single chain antibodies in ALS
Principal Investigator: Charles Krieger, Simon Fraser University
AMOUNT: $100,000.00


ALS Arthur J. Hudson Translational Team Grant

The CANadiAn DynAmic Program of Translational Research for ALS (CAN-ADAPT-ALS)
Principal Investigator: Lawrence Korngut, University of Calgary, Hotchkiss Brain Institute


CQDM - Brain Canada - OBI Focus on Brain

‘Best in Class’ platform for blood brain barrier delivery of therapeutics
Principal Investigator: Danica Stanimirovic, National Research Council of Canada
AMOUNT: $1,495,000.00

Cyto-iGluSnFR: A glutamate biosensor platform for brain diseases
Principal Investigator: Don van Meyel, McGill University, Research Institute of the McGill University Health Centre
AMOUNT: $1,416,375.00

Drug delivery across the human blood-brain barrier
Principal Investigator: Nathan Yoganathan, KalGene Pharmaceuticals Inc
AMOUNT: $1,496,800.00

Human minipromoters for restricted expression of ocular gene therapy
Principal Investigator: Elizabeth Simpson, University of British Columbia
AMOUNT: $1,496,062.00

Non invasive identification of Aß Plaques in human retina for the diagnosis of Alzheimer’s disease
Principal Investigator: Jean-Paul Soucy, McGill University
AMOUNT: $1,500,000.00

Solid phase microextraction-based integrated platform for untargeted and targeted in vivo brain studies
​​​​​​​Principal Investigator: Janusz Pawliszyn, University of Waterloo
AMOUNT: $995,427.00

Barbara Turnbull Award for Spinal Cord Research

Yves De Koninck,Université Laval
AMOUNT: $50,000.00

Dr. Hubert van Tol Travel Fellowship

Nancy Butcher, University of Toronto
AMOUNT: $1,279.00