Directory of funded grants

Developing a “one-two punch” treatment paradigm for targeting glioblastoma

Project Overview

By profiling the protein expression signatures of multiple patient-derived glioblastoma cell lines, we recently identified a major signalling pathway involved in glioblastoma cell migration. Excitingly, we showed that chemical inhibition of a key protein involved in regulating this pathway significantly reduced the infiltration of three glioblastoma cell lines. While inhibiting…