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Our directory of funded grants

217 result(s) found

‘Best in Class’ Platform for Blood Brain Barrier Delivery of Therapeutics

Project Overview

The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases. However, it blocks otherwise effective medicine from reaching the brain. Most drugs developed for treatment of central nervous system diseases fail because they aren’t optimally designed to cro…

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Principal Investigator:
  • Danica Stanimirovic, National Research Council of Canada
Team Members:
  • Reinhard Gabathuler, BiOasis Technologies Inc.
  • Brigitte Guérin, Université de Sherbrooke
  • Roger Lecomte, Université de Sherbrooke
  • David Fortin, Université de Sherbrooke

2012 Barbara Turnbull Award for Spinal Cord Research

Project Overview

Dr. Scott and his research team focus on how feedback to the primary motor cortex, which is a key region in the brain for voluntary control, interacts with spinal activity. This will enable them to understand how sensory feedback from the limb (and vision) is essential while performing voluntary mot…

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Principal Investigator:
  • Stephen Scott, Queen's University

2012 Dr. Hubert van Tol Travel Fellowship

Project Overview

Dr. Jean-François Trempe, is a post-doctoral student at McGill University. Dr. Trempe is working in the lab of Brain Repair Program team member Dr. Ted Fon. His main area of research is on the human gene parkin, whose mutations are known to cause a familial form of Parkinson’s disease. The award …

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Principal Investigator:
  • Jean-Francois Trempe, McGill University

2013 Barbara Turnbull Award for Spinal Cord Research

Project Overview

Although the spinal cord contains all the circuitry necessary for locomotion, due to the absence of commands from the brain, people with spinal cord injuries are unable to walk. Motor recovery can be partially achieved by strategies or therapies intended to regenerate axons from the brain to the spi…

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Principal Investigator:
  • Frederic Bretzner, CHUQ Research Centre, Laval University

2013 Dr. Hubert van Tol Travel Fellowship

Project Overview

Ms. Voronova is a postdoctoral student in the Developmental and Stem Cell Biology Department of The Hospital for Sick Children in Toronto, Ontario.  She used her travel fellowship to attend the  University of Toronto – Karolinska Institute Exchange course in Developmental and Perinatal Biology…

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Principal Investigator:
  • Anastassia Voronova, University of Toronto

2014 Barbara Turnbull Award for Spinal Cord Research

Project Overview

Dr. De Koninck studies the persistent changes in spinal cord function that occur after nervous system injury that lead to chronic pain.  Understanding the long term alterations that occur in the spinal cord after injury will allow Dr. De Koninck and his team to find new treatment and prevention av…

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Principal Investigator:
  • Yves De Koninck, Université Laval

2014 Dr. Hubert van Tol Travel Fellowship

Project Overview

Ms. Nancy Butcher, is a doctoral candidate who is conducting research using advanced brain imaging techniques to measure levels of the brain chemical dopamine, to differentiate between Parkinson’s disease and other motor neuron defects. She used her travel fellowship to attend the PET Tracer Phar…

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Principal Investigator:
  • Nancy Butcher, University of Toronto

2015 Barbara Turnbull Award for Spinal Cord Research

Project Overview

Dr. David and his research team are studying the mechanisms that control the delivery and release of iron in the nervous system. Iron is required for the survival and functioning of nerve cells. However, too much iron can cause damage to nerve cells. Their work has an impact on our understanding of …

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Principal Investigator:
  • Samuel David, McGill University

2015 Dr. Hubert van Tol Travel Fellowship

Project Overview

Dr. Lutz is currently completing his post-doctoral fellowship entitled “Epigenetic mechanisms of childhood maltreatment”, in which he investigates the strong relationship between childhood malnutrition and mental health outcomes. Dr. Lutz’s research focuses on epigenetic analysis of the human …

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Principal Investigator:
  • Pierre-Eric Lutz, McGill University

2016 Dr. Hubert van Tol Travel Fellowship

Project Overview

Through the Hubert van Tol fellowship, Ms. Vecchiarelli was able to attend the International Cannabinoid Research Society (ICRS) Annual Meeting in Bukovina, Poland from June 25-July 1 and the Federation of European Neuroscience Societies (FENS) Forum from July 2-6 in Copenhagen, Denmark, and the Ca…

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Principal Investigator:
  • Hayley Vecchiarelli, University of Calgary

2016 Dr. Hubert van Tol Travel Fellowship

Project Overview

The overarching aim of Ms Morena’s research is to investigate the role of the endocannabinoid system in the modulation of memory processes and its interaction with stress and emotional arousal in animal models of cognition, at a cellular, circuit and behavioural level. Her career goals are: To be …

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Principal Investigator:
  • Maria Morena, University of Calgary

A mixed-methods evaluation of a dance therapy intervention for students seeking on-campus mental health services

Project Overview

Decades of dance research have demonstrated the positive benefits of dance in terms of improving quality of life and reducing symptomatology for diverse groups of participants. Dance may improve mood, body image, self-esteem, and support healing processes for persons suffering from physical, cogniti…

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Principal Investigator:
  • Isabel Fortier, McGill University
Team Members:
  • Sarah Berry, McGill University
  • Joseph FX DeSouza, York University
  • Debora Rabinovich, York University
  • Rebecca Barnstaple, York University

A multi-platform approach to the functional assessment of ASD gene variants

Project Overview

The high and potentially increasing prevalence of Autism Spectrum Disorder (ASD) is taking a significant emotional and economic toll on patients, their families and Canadian society. Although progress has been made in identifying genes associated with ASD, the underlying mechanism of this disorder r…

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Principal Investigator:
  • Kathryn Post, Brain Research Centre, University of British Columbia

A National biobank and database for patients with traumatic brain injury

Project Overview

Traumatic brain injury is the leading cause of death and disability in children and young adults in Canada. Despite huge developments in basic neuroscience, no new therapies or diagnostic tests have been introduced in clinical care over the past 30 years. In the acute setting, neither clinicians nor…

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Principal Investigator:
  • Jamie Hutchison, The Hospital For Sick Children
Team Members:
  • Andrew Baker, St. Michael's Hospital
  • Karen Barlow, Alberta Children's Hospital Research Institute
  • David Clarke, Capital District Health Authority
  • Michael Esser, Alberta Children's Hospital Research Institute
  • Robin Green, Toronto Rehabilitation Institute
  • Anne-Marie Guerguerian, The Hospital For Sick Children
  • Jacques Lacroix, Sainte-Justine University Hospital Centre
  • Alain Ptito, McGill University
  • Keith Walley, James Hogg Research Institute
  • Grant Iverson, University of British Columbia
  • Anthony G. Phillips, University of British Columbia
  • Elizabeth Theriault, University of British Columbia
  • Cheryl Wellington, University of British Columbia
  • Suzanne Vercauteren, BC Children’s Hospital (BCCH)
  • Ash Singhal, BC Children's Hospital and BC Women's Hospital & Health Centre
  • Peter Skippen, BC Children’s Hospital (BCCH)
  • Elaine Gilfoyle, Alberta Children's Hospital Research Institute
  • Ari Joffe, University of Alberta
  • David Zygun, University of Alberta
  • Clare Gallagher, University of Calgary
  • Thomas Sawyer, University of Calgary
  • Sam Weiss, University of Calgary
  • Brent Winston, University of Calgary
  • Greg Hansen, Manitoba Children’s Hospital
  • Murray Kesselman, Manitoba Children’s Hospital
  • Peter Dirks, The Hospital For Sick Children
  • Cynthia Hawkins, The Hospital For Sick Children
  • Angela Colantonio, University of Toronto
  • Karen Choong, McMaster University
  • Alison Fox-Robichaud, McMaster University
  • Patricia Liaw, McMaster University
  • Jane Batt, St. Michaels Hospital
  • Shiva Amiri, Ontario Brain Institute (OBI)
  • Donald Stuss, Ontario Brain Institute (OBI)
  • Douglas Fraser, Children’s Health Research Institute
  • Corinne Kagan, Ontario Neurotrauma Foundation (ONF)
  • Michelle Keightley, Holland Bloorview Kids Rehabilitation Hospital
  • Martin Osmond, Children’s Hospital of Eastern Ontario (CHEO)
  • Roger Zemek, Children’s Hospital of Eastern Ontario (CHEO)
  • Charles H Tator, Krembil Research Institute
  • Catherine Farrell, Sainte-Justine University Hospital Centre
  • Ronald Gottesman, Montreal Children’s Hospital (MCH)
  • Paul Hébert, Centre hospitalier de l'Université de Montréal (CHUM)
  • Bonnie Swaine, Centre hospitalier de l'Université de Montréal (CHUM)
  • Alexis Turgeon, Université Laval
  • Lynne Fenerty, Dalhousie University

A national coordinating neuroinformatics framework for autism and related conditions

Project Overview

New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development. Such approaches dw…

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Principal Investigator:
  • Alan Evans, Montreal Neurological Institute and Hospital, McGill University
Team Members:
  • Mayada Elsabbagh, McGill University
  • Sébastien Jacquemont, Sainte-Justine University Hospital Research Centre
  • Guy Rouleau, Montreal Neurological Hospital and Institute
  • Stephen Scherer, The Hospital For Sick Children
  • Peter Szatmari, Centre for Addiction and Mental Health
  • Evdokia Anagnostou,

    Holland Bloorview Kids Rehabilitation Hospital

  • Teresa Bennett, McMaster University
  • Bruce Pike, Montreal Neurological Hospital and Institute
  • Laurent Mottron, Université de Montréal

A Novel Microfluidic Platform for Investigating Axonal Sprouting in Motor Neurons

Project Overview

Motor neurons are extremely complex cells. Not only do they have an intricate set of inner workings, but they have a long wire-like portion called an axon that connects the central nervous system to muscles called an axon. Understanding all of the aspects of how axons are guided through the body is …

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Principal Investigator:
  • Amir Sanati Nezhad, University of Calgary

A Novel Zebrafish-Based Platform for Anticonvulsant Drug Development

Project Overview

Epilepsy is a common neurological condition that affects 1-2% of the population. Despite dozens of anticonvulsant medications, over a third of patients remain refractory to drugs and our goal is to uncover novel therapies for this patient population. Here, we propose to create a national platform fo…

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Principal Investigator:
  • Deborah Kurrasch, University of Calgary
Team Members:
  • Jong Rho, University of Calgary
  • Jeffrey Buchhalter, University of Calgary
  • Mary Connolly, University of British Columbia

A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Project Overview

Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65. However, a major hindrance in developing therapies for disorders of the brain has been limited access…

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Principal Investigator:
  • Edward Fon, McGill University
Team Members:
  • Guy Rouleau, Montreal Neurological Hospital and Institute
  • Nicolas Dupré, CRCHUQ-Enfant-Jesus, University Laval
  • Tom Pfeifer, Centre for Drug Research and Development
  • Neil Cashman, University of British Columbia
  • Thomas Durcan, Montreal Neurological Institute and Hospital, McGill University
  • Philippe Seguela, McGill University