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774 results found

Early Brain Development Following Prenatal Exposure to SSRI Antidepressants and Maternal Depression

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Mental illness

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    British Columbia

  • Start Date

    2018

  • Total Grant Amount

    $60,000

  • Health Canada Contribution

    $30,000

Project Overview

Many women experience depression during pregnancy, and are often faced with challenging decisions surrounding antidepressant use during this critical time for their developing child. Fetal exposure to maternal antidepressant use is poorly understood, and further, the effects are often left undistinguished from those following exposure to untreated maternal depression. This project has two goals: (1) to determine the effects of antidepressant exposure during pregnancy on the…

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Testing white matter pathway’s influence on neural communication: A combined structural and functional neuroimaging study

  • Grant Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

Ms. Decker will test the hypothesis that myelin damage impairs episodic memory by disrupting neural communication between two memory relevant brain regions, namely, the hippocampus and prefrontal cortex. Accordingly, she will examine neural synchrony, (a measure of neural communication), during an associative encoding and retrieval task in pediatric brain tumor…

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Non-infectious inflammation induced by uric acid during pregnancy and the impact on child neurodevelopment

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

This project focuses on how inflammation, without an infection, can alter brain development when a baby was exposed during pregnancy. Marie-Eve Brien investigates how this sub-optimal prenatal environment programs the developing brain for neurodevelopmental disorders through inflammation in the placenta.

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Enhancing the efficacy of heat shock protein inducers by cotreatment with a histone deacetylase inhibitor – A therapeutic strategy for ALS

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Arthur J. Hudson Translational Team Grant

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $1,727,424

  • Health Canada Contribution

    $863,712

Project Overview

In ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins can become misfolded and clump together, potentially damaging nerve cells. When a healthy body responds to stress, protective mechanisms increase the production of heat shock proteins that help prevent protein misfolding. This mechanism can become…

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Validation of ocular measures as potential biomarkers for early detection of brain amyloid and neurodegeneration

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    The W. Garfield Weston Foundation

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $509,747

  • Health Canada Contribution

    $254,874

Project Overview

500,000 Canadians have dementia, a number that will double within a generation due to the ongoing aging demographics of the population, with annual costs estimated to increase from $15B currently to over $150B by the year 2050. The estimated total cost to the society including the loss of productivity by…

Project Complete

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