Directory of funded grants

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552 results found

Sex-Differences in Dopaminergic Regulation of Stroke Recovery in Rats

  • Program Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Brain Canada-Women’s Brain Health Initiative Expansion Grants: Considering Sex and Gender

  • Province

    Québec

  • Start Date

    2022

  • Total Grant Amount

    $105,000

  • Health Canada Contribution

    $52,500

Project Overview

Strokes often cause brain damage that can severely affect motor function, particularly fine movements of the hands and digits. The motor cortex is the main brain area issuing commands for voluntary hand movements. This brain area, when damaged by a stroke, has the ability to adapt by forming new connections…

HEMO Trial

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    Barbara Turnbull Award for Spinal Cord Research

  • Province

    Alberta

  • Start Date

    2022

  • Total Grant Amount

    $50,000

  • Health Canada Contribution

    $25,000

Project Overview

Spinal cord injury (SCI) leads to dramatic alterations in physical and mental well-being. It is well understood that people with severe SCI lose their ability to move. However, a lesser-known consequence of SCI is the profound disruption to blood pressure (BP) regulation. People with SCI experience rapid fluctuations in their…

Cholinergic & noradrenergic contributions to presymptomatic AD progression

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Québec

  • Start Date

    2022

  • Total Grant Amount

    $188,595

  • Health Canada Contribution

    $85,725

Project Overview

The development of approaches to aid early detection of the transition from healthy aging to mild cognitive impairment and Alzheimer’s disease (AD) is critically important for developing targeted strategies to halt or slow disease progression. Post-mortem studies have identified AD-related brain changes years and even decades before the age of…

Serotonin circuit dysregulation in Alzheimer’s Disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Alberta

  • Start Date

    2022

  • Total Grant Amount

    $190,481

  • Health Canada Contribution

    $86,582

Project Overview

The early and severe loss of serotonin neurons along with the neuroprotective effects of SSRIs in Alzheimer’s Disease (AD) strongly implicates the serotonin system in disease pathology. Yet, mechanisms underlying the vulnerability and contribution of the serotonin system to AD progression remain unknown. Serotonergic impairment early in disease process is…

Electrophysiological measures of proteinopathy in asymptomatic older adults

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Québec

  • Start Date

    2022

  • Total Grant Amount

    $190,378

  • Health Canada Contribution

    $86,537

Project Overview

Our project proposes the development and first-step validation of a new, noninvasive mapping procedure of proteinopathy in asymptomatic older adults. Our approach consists in applying recent advances in magnetoencephalography (MEG) methods that yield the neurophysiological fingerprint of each individual from short recordings of task-free brain activity. We will test the…