Directory of funded grants

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552 results found

Genetic and therapeutic dependencies in SHH driven childhood medulloblastoma

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Medulloblastoma is the most common malignant brain tumour of childhood, affecting 60-80 Canadian children per year. The treatment for medulloblastoma comprises surgery, followed by radiation to the entire brain and spinal cord, and high doses of non-specific chemotherapy. Despite such aggressive treatment, survival is only around 60%, with survivors left…

Project Ongoing

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Investigation of DNA damage response as a genomic modifier in Rett syndrome

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Manitoba

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Rett syndrome is a severe neurological disorder that is caused by genetic mutations in the MECP2 gene. The disorder almost exclusively affects females, presents in childhood and limited effective treatments exist. Since the disease can range in severity and age of onset, there is an active search in the research…

Project Ongoing

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Impact of brain trauma in childhood on white matter maturation

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Brain Injury

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

An enormous amount of brain development occurs throughout childhood and experiencing a concussion during this time may have long-lasting effects. An important part of brain development is the maturation of brain connectivity. Connections in the brain are made up of axons, the long thin projections of nerve cells that are…

Project Ongoing

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Functional hyperalignment in pediatric fMRI

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    British Columbia

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Brain scans from MRI machines are an important research tool for studying psychiatric and neurological disorders in children. MRI lets us study brain structure, and functional MRI (fMRI) lets us also study brain function. In fMRI, each child’s brain images need to be lined up in a special way so…

Project Ongoing

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Evaluation of Long-Axis Hippocampal Subfield Volumetry as a neuroimaging biomarker for Alzheimer’s disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Magnetic resonance imaging can be used to measure these changes in order to improve diagnosis and evaluate potential treatment options for patients with Alzheimer’s disease. The hippocampus is not a uniform brain region,…

Project Ongoing

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