Directory of funded grants

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552 results found

Evaluating therapeutic stimulation in a mouse model of perinatal stroke

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Neonatal strokes occur in approximately 1 in 1500 term births and is the leading cause of hemiplegic cerebral palsy (HCP). The ischemic event leaves most children with life-long motor impairments, and in many cases the effects of rehabilitation are minimal. One potential mechanism for further enhancing the effects of therapy…

Project Ongoing

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Investigating mechanisms that cause mitochondrial dysfunction and synaptic loss

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Amyotrophic lateral sclerosis (ALS) is a fatal disease involving the gradual death of motor neurons. Motor neurons control the body’s movement. As such, their loss leads to muscle weakness, paralysis, and eventually death. Unfortunately, there is no cure or treatments for those living with ALS, in part because the cause…

Project Ongoing

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Impaired orexin activity as a mediator of isolation-induced social anxiety

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

We live in a world profoundly shaped by social behaviours involving interactions and communications between conspecifics of a given species. All mammals, ranging from primates to rodents, depend on each other to survive and reproduce. For children and young adults, neglect and being deprived of social contact are particularly detrimental.…

Project Ongoing

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Investigating Spike-Timing Dependent Plasticity Mechanisms of Memory Consolidation with Multiscale Hippocampal-Cortical Modelling

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The formation of our memories is a behaviour that encapsulates both long-and-short time scales. On the short time-scale, memories are initially formed in the hippocampus through the sequential firing of neurons. These sequences are then replayed by the hippocampus during sleep, where they are thought to be transferred into the…

Project Ongoing

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Investigating the molecular chaperone DNAJA2 as an inhibitor of tau aggregate pathology in Alzheimer’s

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Alzheimer’s Disease is a progressive and fatal disease that currently afflicts up to 400,000 Canadians over the age of 65. One key observation about this disease is that there is an abnormal “clumping” (aggregation) of specific proteins such as tau. Proteins normally need to keep a certain shape to perform…

Project Ongoing

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