Directory of funded grants

Filter by

545 results found

Investigating the role of outer radial glia in autism using human pluripotent stem cells-derived 2D neural cultures and 3D brain organoids

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The extraordinary size and folded shape of the human brain makes us the smartest animal on earth. However, it also means many diseases that harm the human brain disrupt cells and structures that are not seen in other animals such as the mouse, and therefore cannot be adequately studied in…

Challenging epigenetic hallmarks of aging in the choroid plexus to improve brain homeostasis

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The choroid plexus (CP) is a secretory tissue found in each of the brain ventricles. The CP produces a clear fluid called cerebrospinal fluid (CSF) which helps to cushion the brain, to circulate nutrients, and remove waste from our brain. In addition, the CP secretes important molecules involved in the…

Understanding how deviations in postnatal hippocampal neurogenesis and circuit activity contribute to bipolar disorder with patient-derived pluripotent stem cells

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The brain is vulnerable to many disorders that can strike at every stage of life. Bipolar disorder (BD) is a chronic and disabling neuropsychiatric condition that affects 1 in 50 Canadian adults. Like other mental illnesses, BD poses a heavy burden on society due to the cost of care and…

Circadian control of microglial activation in chronic pain states

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Circadian, or 24-hour, rhythms control almost all biological systems in our bodies with sleep-wake cycles and body temperature control the best known examples. Interestingly, pain is also governed by these 24-hour rhythms. People suffering from chronic neuropathic pain have been found to rate their pain as being worse during the…

Modulating attentional circuitry in the anterior cingulate cortex using adaptive intracranial stimulation

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Epilepsy

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Attention is an incompletely understood, complex process that requires precise coordination of brain rhythms within the anterior cingulate cortex (ACC). Children with epilepsy are disproportionately affected by attention deficits. Intracranial electrodes implanted for surgical treatment of epilepsy in this population provide a unique opportunity to safely study and modulate the…