Directory of funded grants

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551 results found

Closed-loop deep brain stimulation using chronic intracranial cortical sensing to inform subcortical stimulation delivery

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Many people with Parkinson's disease have trouble with freezing of gait (FoG), a symptom that causes them to stop walking unexpectedly and makes them more likely to fall. Conventional deep brain stimulation (DBS) has been used to treat FoG, but hasn't been very effective. A new form of DBS, called…

Project Ongoing

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Investigating the role of outer radial glia in autism using human pluripotent stem cells-derived 2D neural cultures and 3D brain organoids

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The extraordinary size and folded shape of the human brain makes us the smartest animal on earth. However, it also means many diseases that harm the human brain disrupt cells and structures that are not seen in other animals such as the mouse, and therefore cannot be adequately studied in…

Project Ongoing

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Challenging epigenetic hallmarks of aging in the choroid plexus to improve brain homeostasis

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The choroid plexus (CP) is a secretory tissue found in each of the brain ventricles. The CP produces a clear fluid called cerebrospinal fluid (CSF) which helps to cushion the brain, to circulate nutrients, and remove waste from our brain. In addition, the CP secretes important molecules involved in the…

Project Ongoing

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Understanding how deviations in postnatal hippocampal neurogenesis and circuit activity contribute to bipolar disorder with patient-derived pluripotent stem cells

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The brain is vulnerable to many disorders that can strike at every stage of life. Bipolar disorder (BD) is a chronic and disabling neuropsychiatric condition that affects 1 in 50 Canadian adults. Like other mental illnesses, BD poses a heavy burden on society due to the cost of care and…

Project Ongoing

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Circadian control of microglial activation in chronic pain states

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Circadian, or 24-hour, rhythms control almost all biological systems in our bodies with sleep-wake cycles and body temperature control the best known examples. Interestingly, pain is also governed by these 24-hour rhythms. People suffering from chronic neuropathic pain have been found to rate their pain as being worse during the…

Project Ongoing

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