Directory of funded grants

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545 results found

Defective protein translation: a causative pathway in ALS?

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    2023 ALS Canada - Brain Canada Trainee Program

  • Province

    British Columbia

  • Start Date

    2023

  • Total Grant Amount

    $75,000

Project Overview

Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43). TDP-43 is an RNA-binding protein that regulates RNA expression and function, including mRNA translation. The mechanisms by which TDP-43 pathology contributes to ALS remain incompletely understood, hampering the development of a rational therapy…

Development of a shared decision-making aid for bulbar symptom management in ALS

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    2023 ALS Canada - Brain Canada Trainee Program

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $50,000

Project Overview

Bulbar disease, which affects speech and swallowing functions, is considered to be one of the most debilitating aspects of ALS by patients. It is characterized by a rapid progression, short survival after diagnosis, and poorer quality of life. Clinical management of bulbar symptoms is focused on optimizing patients’ function and…

Resetting Microglia Activation in Offspring Exposed to Maternal High-Fat Diet

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Master's Personnel Awards for Black Scholars

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $50,000

Project Overview

Nutrition and diet are factors in life that contribute drastically to a person’s brain health, and overall quality of life, and high-fat diets can be considered a cause of many harmful physical and cognitive conditions. In rodent models, exposing the mother to a high-fat diet has been shown to negatively…

Sex-related differences in visuomotor skills, cognition, and emotionality following concussive injury

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    Master's Personnel Awards for Black Scholars

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $10,000

Project Overview

The proposed research project aims to study the differences in brain function behaviour between male and female university athletes who have experienced a concussion. The research will examine hand-eye coordination, thinking and mental processing, and feelings and emotions of these athletes. The research will also investigate the impact of concussion…

How brainstem microstructural integrity relates to decision-making biases in Alzheimer’s Disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Master's Personnel Awards for Black Scholars

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $32,500

Project Overview

The exploration versus exploitation (E&E) decision making trade-off is something we experience every day. Do I return to my favorite restaurant or try something new? Do I watch the same show on Netflix or find a new one? This trade-off between going with what you know, versus trying something new…