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Our directory of funded grants

253 result(s) found

Validation of ocular measures as potential biomarkers for early detection of brain amyloid and neurodegeneration

Project Overview

500,000 Canadians have dementia, a number that will double within a generation due to the ongoing aging demographics of the population, with annual costs estimated to increase from $15B currently to over $150B by the year 2050. The estimated total cost to the society including the loss of productivi…

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Principal Investigator:
  • Sandra Black, Sunnybrook Health Sciences Centre
Team Members:
  • Anthony Lang, Krembil Research Institute
  • Chris Hudson , University of Waterloo
  • Lee Goldstein, Boston University
  • Barry Greenberg, Krembil Research Institute
  • Efrem Mandelcorn, Krembil Research Institute
  • Edward Margolin, Krembil Research Institute
  • Stephen Strother, Rotman Research Institute
  • Aristotle Voineskos, Centre for Addiction and Mental Health

Project Completed

Program Type:

Team grants

Area of Research:

Neurodegenerative

Competition:

The W. Garfield Weston Foundation

Province:

Ontario

Start Date: 2014

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Wnt Signalling Circuits in Glioma Progression

Project Overview

The goal of Ms. Rajakulendran’s project is to characterize the role of Wnt signalling in glioma progression. The primary objective is to determine whether glioblastoma multiforme (GBM) is dependent on Wnt signalling for cancer stem cell self-renewal. The secondary objective is to identify the Wnt …

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Principal Investigator:
  • Nishani Rajakulendran, University of Toronto

Project Completed

Program Type:

Capacity building grants

Area of Research:

Brain Cancer

Competition:

Brain Canada - CIBC Brain Cancer Research Training Awards

Province:

Ontario

Start Date: 2013

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Z-BRAIN: A Zebrafish Drug Screening Platform Targeting Brain Disorders

Project Overview

The traditional target-based drug development strategy (in vitro screening) has had poor success in developing new drugs. The vast majority of Investigational New Drugs (INDs) fail in clinical trials due to toxicity or lack of efficacy. On the other hand, mammalian models are excellent tools to stud…

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Principal Investigator:
  • Xiao-Yan Wen, St. Michael's Hospital
Team Members:
  • Pierre Drapeau, CHUM Research Centre, University of Montréal
  • Raymond Andersen, University of British Columbia
  • Robert Gerlai, University of Toronto
  • Georg Zoidl, York University
  • Loch Macdonald, St. Michael's Hospital
  • Andrew Baker, St. Michael's Hospital
  • Albert Wong, Centre for Addiction and Mental Health
  • Marc Ekker, University of Ottawa
  • Sidney H. Kennedy, University Health Network
  • Alan Fine, Dalhousie University
  • Janice Robertson, University of Toronto
  • Vince Tropepe, University of Toronto
  • Henry Krause, University of Toronto
  • Terry Van Raay, University of Guelph
  • Tom Schweizer, St. Michael's Hospital
  • David Munoz, St. Michael's Hospital
  • Corinne Fischer, St. Michael's Hospital
  • Thomas Steeve, St. Michael's Hospital
  • Ted Allison, University of Alberta
  • Cheryl Gregory-Evans, University of British Columbia
  • Claudia dos Santos, St. Michael's Hospital

Project Completed

Program Type:

Platform grants

Area of Research:

Multiple

Competition:

2014 Platform Grants

Province:

Ontario

Start Date: 2015

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