Directory of funded grants

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545 results found

Zebrafish as a novel animal model for the study of Zika virus neuropathogenesis in vivo

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Infections with Zika virus (ZIKV) constitute a major global public health concern worldwide. Indeed, the recent ZIKV outbreak in the Americas revealed that infection of pregnant women can lead to congenital transmission, infection within the fetal developing brain and eventually to microcephaly in the infant. Most importantly, no antiviral therapies…

Direct microglial reprogramming to study Parkinson’s Disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson'sAlzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The human brain is a complex organ that presents many challenges for neuroscientists. For instance, tissue availability represents a major problem given that this organ does not regenerates, making it next to impossible to obtain live tissue from patients that would allow to study how cells in the brain change…

Dopaminergic modulation of stroke recovery

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Strokes often cause brain damage that affects normal cognitive and sensorimotor functions. The brain has the extraordinary ability to adapt by forming new circuits which can, to some extent, compensate for neuronal loss. The recovery of motor function can be improved by rehabilitation exercises aimed at strengthening the brain and…

Molecular origins of childhood brain cancer

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Pediatric high-grade gliomas are incurable brain cancers. Sequencing the tumor specimens has shown that most cases do not have obvious mutations that are known to cause cancer. It is therefore not known what causes, or "drives," these cancers. Identifying cancer drivers is a fundamental step in designing new treatments. We…

Individually Tailored Prediction of Treatments Response in Alzheimer’s Disease: 3 clinical trials validation

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Late-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with abnormalities in toxic protein accumulation, vascularization, inflammation, neuronal activity and cerebral atrophy. In keeping with the tenets of Personalized Medicine, treatments should be tailored to individual therapeutic needs as opposed to treating all patients with the same approach. In Neurodegeneration, unfortunately,…