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Our directory of funded grants

288 result(s) found

The role of peripheral inflammation in ALS: an exploratory study

Project Overview

It has been more than a decade since scientists proved that ALS is not simply a disease of motor neurons, but that other cells in the neighbourhood around them could play an active role in the disease process. A series of intricate experiments demonstrated that genetically ‘turning off’ ALS in m…

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Principal Investigator:
  • Fabio Rossi, University of British Columbia

The Role of Translational Control in Cortical Dysgenesis in Mammalian Brain

Project Overview

Dr. Yang is studying genetic mechanisms that alter brain development at a molecular and cellular level, leading to changes implicated in autism spectrum disorder. He does this by studying messenger RNA translation. Previously, Dr. Yang had focused on the elF4E gene, a regulator of mRNA translation, …

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Principal Investigator:
  • Guang Yang, The Hospital For Sick Children

The Toronto Dementia Research Alliance (TDRA) Dementia Clinical Research Database: A Platform in Neurodegenerative Diseases

Project Overview

The Toronto Dementia Research Alliance will establish a clinical research platform that will provide a consistent and efficient approach to managing research and clinical care in patients with neurodegenerative conditions. The platform will provide epidemiological data, track disease burden, fill ga…

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Principal Investigator:
  • Morris Freedman, Rotman Research Institute
Team Members:
  • Stephen Strother, Rotman Research Institute
  • David Tang-Wai, University Health Network
  • Sandra Black, Sunnybrook Health Sciences Centre
  • Mario Masellis, Sunnybrook Health Sciences Centre
  • Corinne Fischer, St. Michael's Hospital
  • Alan Moody, Sunnybrook Health Sciences Centre
  • Paula Rochon, Women's College Hospital
  • Carmela Tartaglia, University Health Network
  • Nathan Herrmann, Sunnybrook Health Sciences Centre
  • Barry Greenberg, Krembil Research Institute
  • Donald Weaver, Toronto Western Research Institute, University of Toronto
  • Ron Keren, University Health Network
  • Barry Goldlist, University Health Network
  • Uri Wolf, Baycrest
  • Paul Verhoeff, Baycrest
  • Gary Naglie, Baycrest
  • A. Randy MacIntosh, Rotman Research Institute
  • William Reichman, Baycrest
  • Sanjeev Kumar, Centre for Addiction and Mental Health
  • Tarek Rajji, Centre for Addiction and Mental Health
  • Benoit Mulsant, CAMH, University of Toronto
  • Suvendrini Lena, Centre for Addiction and Mental Health
  • Sean Symons, Sunnybrook Health Sciences Centre
  • Krista Lanctot, Sunnybrook Health Sciences Centre
  • Walter Montanera, St. Michael's Hospital
  • Angie Troyer, Baycrest
  • Tom Schweizer, St. Michael's Hospital
  • Kathryn Stokes, Baycrest
  • Mary-Pat McAndrews, University Health Network
  • Prathiba Shammi, Sunnybrook Health Sciences Centre
  • Linda Mah, Rotman Research Institute, Baycrest Centre
  • Wendy Lou, University of Toronto
  • Kevin Thorpe, University of Toronto
  • Pascal Tyrrell, University of Toronto
  • Bruce Pollock, Centre for Addiction and Mental Health
  • Alex Kiss, Sunnybrook Health Sciences Centre
  • Malcolm Binns, Baycrest Health Sciences
  • Tamara Arenovich, Centre for Addiction and Mental Health
  • Susan Bronskill, ICES
  • Cheryl Grady, Baycrest
  • General Leung, St. Michael's Hospital
  • Sapna Rawal, University Health Network
  • David Mikulis, University Health Network

Three-dimensional Video-based Analysis of Infant’s Movements for Early Detection of Motor Impairment

Project Overview

This project is focused on the development of novel technologies to support clinicians in the assessment and diagnosis of cerebral palsy and motor impairment by studying infants’ movements in the first months of life. Silvia Orlandi will compare atypical and typical spontaneous movements using co…

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Principal Investigator:
  • Silvia Orlandi, Holland Bloorview Kids Rehabilitation Hospital

Toward exercise as medicine for adolescents with bipolar disorder

Project Overview

This project focuses on improving aerobic fitness (AF) among adolescents with bipolar disorder (BD). BD affects 2-5% of adolescents and is the 4th most disabling medical condition among adolescents worldwide. Even with treatment, adolescents with BD spend over half of the time with mood symptoms tha…

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Principal Investigator:
  • Benjamin Goldstein, Sunnybrook Research Institute
Team Members:
  • Brian McCrindle, The Hospital for Sick Children
  • Guy Faulkner, University of British Columbia
  • Rachel Mitchell, Sunnybrook Research Institute
  • Bradley MacIntosh, Sunnybrook Research Institute
  • Andrew Kcomt, Mood Disorders Association of Ontario and Toronto
  • Erin Michalak, University of British Columbia