Directory of funded grants

Filter by

551 results found

Individually Tailored Prediction of Treatments Response in Alzheimer’s Disease: 3 clinical trials validation

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Late-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with abnormalities in toxic protein accumulation, vascularization, inflammation, neuronal activity and cerebral atrophy. In keeping with the tenets of Personalized Medicine, treatments should be tailored to individual therapeutic needs as opposed to treating all patients with the same approach. In Neurodegeneration, unfortunately,…

Project Complete

See the project and researchers

Molecular and behavioural assessment of a potential fetal Cannabis spectrum disorder in the rat

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Saskatchewan

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Canada recently became the first G7 nation to legalize Cannabis for medicinal and recreational use. There is a recent and growing false belief that Cannabis can reduce nausea during pregnancy without harmful side effects on the fetus. This belief is not based in scientific research, of which there is very…

Project Complete

See the project and researchers

Relating hippocampal pathways to human learning

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The human experience is marked by constant learning. Moments of contention, when new experiences conflict with prior knowledge, often lead to the most meaningful learning. How do we successfully navigate these moments and gain new knowledge? In the current project, we aim to answer this question by characterizing (1) how…

Project Ongoing

See the project and researchers

The endocannabinoid system: a master regulator of brain and gut health in mood disorders

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Depression will affect 1 out of 5 individuals in their lifetime. Antidepressant treatments are not effective for 30-50% patients, only 30% completely remit and do not suffer from another depressive episode, suggesting that current therapies do not address important biological mechanisms involved such as neurovascular dysfunction or inflammation, which are…

Project Ongoing

See the project and researchers

Investigation of neuroinflammation and microglial subtypes associated with ALS

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The common end stage pathology of neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) is neuronal death. Several decades of basic research have focused on investigating the mechanisms underlying neuronal death and dysfunction. Accumulating studies showed that neuroinflammation is correlated with disease progression, suggesting…

Project Complete

See the project and researchers