Directory of funded grants

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552 results found

Molecular origins of childhood brain cancer

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Pediatric high-grade gliomas are incurable brain cancers. Sequencing the tumor specimens has shown that most cases do not have obvious mutations that are known to cause cancer. It is therefore not known what causes, or "drives," these cancers. Identifying cancer drivers is a fundamental step in designing new treatments. We…

Individually Tailored Prediction of Treatments Response in Alzheimer’s Disease: 3 clinical trials validation

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Late-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with abnormalities in toxic protein accumulation, vascularization, inflammation, neuronal activity and cerebral atrophy. In keeping with the tenets of Personalized Medicine, treatments should be tailored to individual therapeutic needs as opposed to treating all patients with the same approach. In Neurodegeneration, unfortunately,…

Molecular and behavioural assessment of a potential fetal Cannabis spectrum disorder in the rat

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Saskatchewan

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Canada recently became the first G7 nation to legalize Cannabis for medicinal and recreational use. There is a recent and growing false belief that Cannabis can reduce nausea during pregnancy without harmful side effects on the fetus. This belief is not based in scientific research, of which there is very…

Relating hippocampal pathways to human learning

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The human experience is marked by constant learning. Moments of contention, when new experiences conflict with prior knowledge, often lead to the most meaningful learning. How do we successfully navigate these moments and gain new knowledge? In the current project, we aim to answer this question by characterizing (1) how…

The endocannabinoid system: a master regulator of brain and gut health in mood disorders

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Depression will affect 1 out of 5 individuals in their lifetime. Antidepressant treatments are not effective for 30-50% patients, only 30% completely remit and do not suffer from another depressive episode, suggesting that current therapies do not address important biological mechanisms involved such as neurovascular dysfunction or inflammation, which are…