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552 results found

Investigation of neuroinflammation and microglial subtypes associated with ALS

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The common end stage pathology of neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) is neuronal death. Several decades of basic research have focused on investigating the mechanisms underlying neuronal death and dysfunction. Accumulating studies showed that neuroinflammation is correlated with disease progression, suggesting…

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Neuroprosthetic-mediated rehabilitation of autonomic function after spinal cord injury

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Spinal cord injury (SCI) is a devastating medical condition that forever changes the trajectory of life. It is also costly to the health care system, similar to traumatic brain injury or Alzheimer’s. Perhaps surprisingly, people with SCI report autonomic (i.e., automatic/unconscious) issues such as cardiovascular dysfunction as a more important…

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Mapping neuronal circuits using a novel transsynaptic labelling approach

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The brain is more than the sum of its parts. Truly understanding the brain's most intricate properties requires both a list of its individual parts, that is a census of the types of neurons it contains, and a map of how these parts are interconnected to form neural circuits. Hundreds…

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Tanycytic structural plasticity in circumventricular organs underlies homeostatic brain-body communication

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Metabolic syndrome is a group of risk factors (obesity, hypertension, high fasting blood sugar, and high levels of triglycerides) that increase the risk of type 2 diabetes and cardiovascular diseases. Over 20% of adult Canadians suffer from metabolic syndrome (40% in adults over 60 years old), and effective treatments are…

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Laminar regulation of hemodynamics in primary auditory cortex

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Brain disorders and disease represent an immense societal burden and the leading cost to the Canadian health care system. Although research in animal models has led to major advances in our understanding of brain function and dysfunction at the cellular level, a major challenge remains bridging these findings from animals…

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