Directory of funded grants

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740 results found

MitoDREADD-Gs: a new tool to identify the cell type-specific causal mechanisms in dementia

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    New Brunswick

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Mitochondria are cellular components which provide the energy required by the brain. Any alteration of these small engines can lead to brain disorders, but their role in dementia remains poorly understood. We developed a tool named mitoDREADD-Gs. MitoDREADD-Gs is a transmembrane receptor which can be expressed in brain mitochondria of…

Project Ongoing

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Subvention pour validation de concept

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    British Columbia

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Les tests génétiques montrent que le gène tau peut souvent induire des changements (mutations d’ADN) chez les personnes vivant avec des troubles neurocognitifs, mais aussi chez les personnes pour lesquelles ce diagnostic n’a pas encore été établi. Toutefois, les médecins ne savent pas si la plupart de ces changements contribuent…

Project Ongoing

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Using Alzheimer’s blood biomarkers to evaluate the effect of photobiomodulation in patients with Mild Cognitive Impairment

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Every day, over 350 Canadians are diagnosed with dementia, and this number is expected to grow rapidly. Mild Cognitive Impairment (MCI) is an early stage where memory problems begin, and about one-third of people with MCI develop dementia. Our study is testing a new, non-invasive treatment called transcranial photobiomodulation (tPBM),…

Project Ongoing

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Exploring the complexities of dementia risk in females: role of pregnancy history and the gut-brain axis

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Alberta

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history. For example, the number of pregnancies a woman has had may influence her brain health after menopause, but the biological reasons remain unclear. We believe gut health — shaped by…

Project Ongoing

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Targeting a keystone bacterial periodontal pathogen to mitigate neurodegenerative changes in Alzheimer’s disease

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Periodontal disease has links with Alzheimer’s disease. The bacterium Porphyromonas gingivalis plays a major role in gum disease and has been associated with Alzheimer’s disease. We have identified a small protein, produced by the healthy gum around teeth, called SCPPPQ1, which has been shown to kill this bacterium. Our goal…

Project Ongoing

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