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552 results found

Stability-Based Biomarker Development to Identify Pathological Brain Areas Responsible for Freezing of Gait in Parkinson’s Disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Brain Canada Next Gen Award in Parkinson’s Disease Research

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $12,000

  • Health Canada Contribution

    $6,000

Project Overview

Brain stimulation involves using electrical or magnetic pulses to treat medical disorders like Parkinson's by sending controlled pulses to the brain in order to manage patient symptoms. Even though brain stimulation has been quite successful and is widely accepted, there are still important things that remain unknown. One of the…

Project Ongoing

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Intraoperative Identification of Residual Brain Tumour Using a Novel High-Resolution Ultrasound Endoscope and Integrated Neuronavigation System

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Henry and Berenice Kaufmann Foundation Trainee Award in Brain Cancer Research

  • Province

    Nova Scotia

  • Start Date

    2023

  • Total Grant Amount

    $12,000

  • Health Canada Contribution

    $6,000

Project Overview

20,800 North Americans die from brain cancer each year. This project aims to improve patient outcomes by helping surgeons remove tumours with higher accuracy and less damage to healthy brain. When removing brain tumours, surgeons guide the operation visually and with a microscope. This can be challenging as the path…

Project Ongoing

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Mechanisms of response and resistance to Olaparib and Durvalumab in treatment of glioblastomas and IDH-mutated astrocytomas

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Henry and Berenice Kaufmann Foundation Trainee Award in Brain Cancer Research

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $10,000

  • Health Canada Contribution

    $5,000

Project Overview

Glioblastoma multiforme and high grade astrocytomas are aggressive brain tumors that are difficult to treat. These tumors have genetic changes that affect their ability to repair DNA. Recent research has discovered that a combination of two drugs, Olaparib and Durvalumab, could be effective in treating these tumors. Olaparib blocks a…

Project Ongoing

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Leveraging proximity interactomics to identify therapeutically targetable RNA-binding proteins in G4C2 repeat-driven ALS

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    Pierre Auger Morissette Capacity-Building Award in ALS Research

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $7,500

  • Health Canada Contribution

    $3,750

Project Overview

Amyotrophic lateral sclerosis (ALS) is a progressive disease that causes loss of control over muscles and leads to death quickly after diagnosis. It remains incurable, with a subtype of ALS being commonly associated with a specific genetic mutation that causes a toxic RNA molecule to be produced. This repeat-containing RNA…

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Investigating cerebellar Pathology in a zebrafish C9orf72 ALS model

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    Pierre Auger Morissette Capacity-Building Award in ALS Research

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $7,500

  • Health Canada Contribution

    $3,750

Project Overview

Amyotrophic Lateral Sclerosis (ALS) is a rare and fatal disease, which is characterized by degeneration of specific neurons called “Motor neurons” that control the movement of our muscles. We are particularly interested in a specific gene called C9ORF72, which is found to be mutated in most of the ALS cases.…

Project Ongoing

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