Répertoire des subventions financées

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558 ésultat(s) trouvé(s)

Investigating the molecular chaperone DNAJA2 as an inhibitor of tau aggregate pathology in Alzheimer’s

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Date de Début

    2021

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Alzheimer’s Disease is a progressive and fatal disease that currently afflicts up to 400,000 Canadians over the age of 65. One key observation about this disease is that there is an abnormal “clumping” (aggregation) of specific proteins such as tau. Proteins normally need to keep a certain shape to perform…

Projet en cours

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Cognition and Functional Specialization in Connectome-Based Neuromorphic Networks

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2021

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

How does the wiring of the brain confer cognitive capacity? Technological, analytic, and theoretical advances present a unique opportunity to reconstruct brain networks in individuals. At the same time, modern artificial intelligence algorithms offer new ways to link structure and function, by conceptualizing function as a computational property. Despite common…

Projet en cours

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Closed-loop deep brain stimulation using chronic intracranial cortical sensing to inform subcortical stimulation delivery

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2021

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Many patients with Parkinson’s disease experience freezing of gait (FoG), a debilitating symptom defined by “episodic absences or marked reduction of forward progression of the feet despite the intention to walk.” FoG can lead to reduced mobile independence and increased risk of falls, which can cause serious injury or even…

Projet en cours

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Investigating the role of outer radial glia in autism using human pluripotent stem cells-derived 2D neural cultures and 3D brain organoids

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Disease Area

    Autism

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2022

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The extraordinary size and folded shape of the human brain makes us the smartest animal on earth. However, it also means many diseases that harm the human brain disrupt cells and structures that are not seen in other animals such as the mouse, and therefore cannot be adequately studied in…

Projet en cours

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Challenging epigenetic hallmarks of aging in the choroid plexus to improve brain homeostasis

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2021

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The choroid plexus (CP) is a secretory tissue found in each of the brain ventricles. The CP produces a clear fluid called cerebrospinal fluid (CSF) which helps to cushion the brain, to circulate nutrients, and remove waste from our brain. In addition, the CP secretes important molecules involved in the…

Projet en cours

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