Répertoire des subventions financées

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Individually Tailored Prediction of Treatments Response in Alzheimer’s Disease: 3 clinical trials validation

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2020

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Late-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with abnormalities in toxic protein accumulation, vascularization, inflammation, neuronal activity and cerebral atrophy. In keeping with the tenets of Personalized Medicine, treatments should be tailored to individual therapeutic needs as opposed to treating all patients with the same approach. In Neurodegeneration, unfortunately,…

Molecular and behavioural assessment of a potential fetal Cannabis spectrum disorder in the rat

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodevelopment

  • Disease Area

    Other

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Saskatchewan

  • Date de Début

    2020

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Canada recently became the first G7 nation to legalize Cannabis for medicinal and recreational use. There is a recent and growing false belief that Cannabis can reduce nausea during pregnancy without harmful side effects on the fetus. This belief is not based in scientific research, of which there is very…

Relating hippocampal pathways to human learning

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Central Nervous System

  • Disease Area

    Autism

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2020

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The human experience is marked by constant learning. Moments of contention, when new experiences conflict with prior knowledge, often lead to the most meaningful learning. How do we successfully navigate these moments and gain new knowledge? In the current project, we aim to answer this question by characterizing (1) how…

The endocannabinoid system: a master regulator of brain and gut health in mood disorders

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Mental Health

  • Disease Area

    Mental illness

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Date de Début

    2020

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

Depression will affect 1 out of 5 individuals in their lifetime. Antidepressant treatments are not effective for 30-50% patients, only 30% completely remit and do not suffer from another depressive episode, suggesting that current therapies do not address important biological mechanisms involved such as neurovascular dysfunction or inflammation, which are…

Investigation of neuroinflammation and microglial subtypes associated with ALS

  • Type de programme

    Capacity building grants

  • Domaine de recherche

    Neurodegeneration

  • Disease Area

    ALS FR

  • Compétition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Date de Début

    2020

  • Montant total du financement

    $100,000

  • Contribution Santé Canada

    $50,000

Aperçu du projet

The common end stage pathology of neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) is neuronal death. Several decades of basic research have focused on investigating the mechanisms underlying neuronal death and dysfunction. Accumulating studies showed that neuroinflammation is correlated with disease progression, suggesting…