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A Novel Microfluidic Platform for Investigating Axonal Sprouting in Motor Neurons

Principal Investigator:
  • Amir Sanati Nezhad, University of Calgary
  • ALS Society of Canada

Project Overview

Motor neurons are extremely complex cells. Not only do they have an intricate set of inner workings, but they have a long wire-like portion called an axon that connects the central nervous system to muscles called an axon. Understanding all of the aspects of how axons are guided through the body is important and as yet poorly understood. Dr. Amir Sanati Nezhad of the University of Calgary will develop a specialized chamber called a microfluidic device that will allow the unique ability to study axons and to apply substances at specific places along their length to better understand the disease and potentially to treat it.