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The feasibility of hyperpolarized 13C-Pyruvate MRI for monitoring patients with intracranial metastasis

Principal Investigator:
  • Charles Cunningham, Sunnybrook Research Institute
  • Canadian Cancer Society

Project Overview

Surgery and radiation are standard treatments for cancer that has spread to the brain. Recent research has revealed that cancer cells with high levels of the chemical lactate are aggressive and resist radiation therapy. Dr Charles Cunningham will study whether an enhanced imaging method that can detect lactate can help predict how cancer in the brain will behave. He will compare it to other routine imaging techniques used to assess patients before brain radiation therapy. This new method may help tailor treatment plans to prolong survival. This grant is funded in partnership with Brain Canada with the financial support of Health Canada.