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Wnt Signalling Circuits in Glioma Progression

Principal Investigator:
  • Nishani Rajakulendran, University of Toronto

Project Overview

The goal of Ms. Rajakulendran’s project is to characterize the role of Wnt signalling in glioma progression. The primary objective is to determine whether glioblastoma multiforme (GBM) is dependent on Wnt signalling for cancer stem cell self-renewal. The secondary objective is to identify the Wnt receptor complex important in this context.