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Our directory of funded grants

34 result(s) found

A multi-platform approach to the functional assessment of ASD gene variants

Project Overview

The high and potentially increasing prevalence of Autism Spectrum Disorder (ASD) is taking a significant emotional and economic toll on patients, their families and Canadian society. Although progress has been made in identifying genes associated with ASD, the underlying mechanism of this disorder r…

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Principal Investigator:
  • Kathryn Post, Brain Research Centre, University of British Columbia

An Evaluation of the Acceptability of the Family Check-Up Intervention for Caregivers of Young Children with Autism Spectrum Disorders

Project Overview

This project looks at the acceptability of the Family Check-up (FCU) program for caregivers of children with Autism Spectrum Disorder (ASD). The Family Check-up is a brief, evidence-based, assessment-driven intervention that uses a strength-based and motivational interviewing approach to engage care…

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Principal Investigator:
  • Vivian Lee, McMaster University

Brain-Computer Interface Integrated Augmentative and Alternative Communication

Project Overview

This projects looks at a new method to interface with communication devices through brain activity. A brain interface provides access for individuals with brain injury, or who are not typically developing, who experience limited voluntary muscle control.  Kaela Shea will investigate the possibilit…

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Principal Investigator:
  • Kaela Shea, Holland Bloorview

Characterization of a novel medulloblastoma tumor suppressor

Project Overview

Medulloblastoma is a pediatric cancer of the brain and is the most common solid tumour in children. Currently, the standard therapy for medulloblastoma remains nonspecific to the cancer subtype and consists of surgery followed by chemotherapy and/or craniospinal irradiation. Due to these treatments,…

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Principal Investigator:
  • Sabrina Schlienger, IRCM

Co-clinical trials of autism in mice and humans

Project Overview

Autism is a neuro-developmental disorder characterized by social/communication deficits and repetitive behaviours. It is very heterogeneous, with over 250 genes implicated, but is highly heritable. The current therapeutic approach is frequently ineffective partly because often a single treatment is …

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Principal Investigator:
  • Zsuzsa Buchwald, University of Toronto