Directory of funded grants

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775 results found

Functional investigation of a novel genetic player in brain development

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The human brain’s development relies on precisely coordinated genetic programs that ensure proper wiring and function. When these processes go awry, neurodevelopmental disorders, including severe epileptic encephalopathies, can arise. Lennox-Gastaut Syndrome (LGS) is a rare and severe childhood epilepsy that is often resistant to current treatments, suggesting the involvement of…

Discovering “hidden” causal mutations in autism using long-read RNAseq and proteomics in neuron development

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Autism spectrum disorder (ASD) is a complex condition affecting communication, social interactions, and behavior in approximately 1–2% of people worldwide. While some cases of ASD can be linked to specific genetic changes, most remain unexplained, leaving families and clinicians without clear answers. Recent studies suggest that our current understanding of…

Examining the neurobiological substrates of antidepressant effects of psilocybin: a PET imaging study using SYNVEST1

  • Grant Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. BD is characterized by recurrent episodes of depression and (hypo)mania. Many people do not improve when they receive a recommended treatment, leading to treatment resistance. Psilocybin has been identified as a potential option to…

Utilizing next generation intersectional approaches to define the roles of POMC neuron subpopulations

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The central nervous system controls numerous processes, including appetite and body weight regulation. Given the alarming rise in global obesity, understanding how the CNS controls appetite is crucial. Among the cell types involved, neurons expressing the gene "Pro-opiomelanocortin" (POMC) are particularly important. Loss of POMC neurons or the POMC gene…

First-Principle modeling of Diffusion MRI in Brain tumor

  • Grant Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Glioblastoma is the most common primary malignant brain tumor in the adult population with a very poor prognostic. The combination of surgery, chemotherapy and radiotherapy are used as treatment. Magnetic Resonance Imaging (MRI) is used to delineate the disease before surgery and to monitor patients after surgery. Two of the…