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Stearoyl-CoA Desaturases in Neurodegeneration and Immunity in Parkinson’s Disease

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Parkinson’s disease (PD) is a serious brain disorder that affects movement, and quality of life for over 10 million people worldwide. Current treatments ease symptoms but do not slow or stop the disease. To develop better therapies, we need to understand the underlying biological processes that drive PD. One promising…

Decoding Regional Neuroinflammation in Alzheimer’s Disease Through Seeding–Proteome–Spatial Integration

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Ontario

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Alzheimer’s disease (AD) affects nearly one million Canadians and remains without a cure. Although most research has focused on the build-up of abnormal proteins such as amyloid and tau, we now know that inflammation in the brain’s immune system plays a major role in how the disease starts and progresses.…

Untangling the adaptive immune response in PD

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Parkinson’s disease (PD) is a common brain disorder that gradually affects movement, balance, and coordination. It mainly results from the loss of nerve cells that produce dopamine, a chemical that helps control motion. Although inflammation in the brain has long been observed in people with PD, scientists still do not…

Pharmacological Inhibition of TRPM2 in Neuroinflammation & Infection Models 

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Ontario

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Alzheimer’s Disease (AD) is a neurodegenerative disorder that affects a growing population and poses a significant public health challenge. It is characterized by cognitive decline and memory loss, of which current therapies only manage symptoms or slow disease progression and does not treat the underlying disease progression. Therefore, there is…

Peripheral immune signatures of neurodegeneration in isolated REM sleep behavior disorder: an MRI-neuroinflammation study

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

When we dream, our bodies are normally paralyzed so we don’t act out the dream. In isolated REM sleep behavior disorder (iRBD), that safety switch fails: people may talk, shout, punch, or kick during sleep. iRBD is important because most people with it will later develop a brain disease like…