720 results found
Le Consortium d’Imagerie en Neurosciences et santé mentale de Québec: leader régional en neuroimagerie humaine
Project Overview
Le Consortium d’Imagerie en Neurosciences et santé mentale de Québec (CINQ) est un regroupement de chercheurs pluridisciplinaires ayant pour but le développement de la neuroimagerie dans la région de Québec. Depuis sa création en 2009, le CINQ a connu un taux de croissance fulgurant, passant de quatre à 138 chercheurs…
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See the project and researchersEarly Postnatal Metabolic Treatment for the Fetal Alcohol Syndrome
Project Overview
Fetal Alcohol Syndrome (FAS) is the result of in utero alcohol exposure and is characterized by central nervous system developmental impairments which causes lifelong physical and cognitive disabilities. The mechanisms of the impaired brain development are poorly understood, but they seem to be related with the decreased levels of antioxidants…
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See the project and researchersCo-clinical trials of autism in mice and humans
Project Overview
Autism is a neuro-developmental disorder characterized by social/communication deficits and repetitive behaviours. It is very heterogeneous, with over 250 genes implicated, but is highly heritable. The current therapeutic approach is frequently ineffective partly because often a single treatment is given to a heterogeneous patient population. This project will address the…
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See the project and researchersIn vitro and in vivo functional assessment of neuropsychiatric disease-related synaptic gene mutations
Project Overview
Dr. Xie’s research focuses on the functional assessment of neuropsychiatric disease related synaptic genes – MDGA1 and 2. MDGAs bind to critical neuron synaptic proteins – Neuroglin (NLGN), disrupting the binding between NLGN and Neurexin (NRXN), so suppressing synaptogenesis. Mutations (missense or truncation) of MDGA1 and 2 have been found…
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See the project and researchersRecruitment of Endogenous Neural Stem Cells to Promote Brain Repair Following Acquired Brain Injury in Children
Project Overview
In Canada, over 140,000 children and teenagers suffer a brain injury each year due to trauma, stroke, cerebral palsy, and brain cancer. Children are often left with permanent physical, psychological, and neurological problems. Currently, there are no effective medical therapies to help brain recovery and reduce disability following an acquired…