Directory of funded grants

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552 results found

Targeting GRP78 palmitoylation in glioblastomas

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Glioblastoma multiforme (GBM) the most common form of brain cancer in adults with very low survival of only 15 months with less than 5% of patients surviving more than 5 years. Surgery, chemotherapy, and radiation are the treatments currently used but recurrence is very common, often with tumors that are…

Project Ongoing

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Evaluating an innovative e-mental health solution to support youth with mental health disorders in Northwestern Ontario

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Many youth suffer from mental health-related brain disorders which can have devastating consequences Effective treatment is desperately needed. Youth in underserviced areas such as Northwestern Ontario have increased need for and decreased access to mental health treatment, especially those in rural and remote areas. Limited access and longer waits for…

Project Ongoing

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Investigating the role of microglia in brain disorders, by high-throughput single-cell screening of disease-associated genes in human immuno-competent brain avatars

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s,  Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Most brain disorders remain incurable, whether they begin during early development, as seen in Autism, or seem acquired over time, as observed in Alzheimer’s disease. Population studies have now pointed to hundreds of DNA variants as possible culprits in these disorders and have highlighted the role of immunity. The functional…

Project Ongoing

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Somatic mutations causing focal epilepsy identified using purified neuronal nuclei from stereo-EEG electrodes

  • Program Type

    Capacity building grants

  • Area of research

    Seizure

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Patients with epilepsy have recurrent seizures that lead to injuries, social issues, job and driving restrictions and even death. The cause of epilepsy is often unknown but recent studies have suggested that genetic changes in brain cells that are not inherited but occur during fetal development can cause epilepsy. As…

Project Ongoing

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Defining the role of primary cilia in shaping astrocyte development and response to brain insults

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Astrocytes are a major type of cells that react to brain activity, injuries and diseases to help support optimal brain functions. It is increasingly recognized that astrocyte dysfunction is a leading cause of almost all major neurological disorders. These findings have stimulated excitements that astrocyte-based transplant cell therapy and drug…

Project Ongoing

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