Directory of funded grants

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661 results found

Repairing nerve cell connections in Alzheimer’s disease

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    British Columbia

  • Start Date

    2023

  • Total Grant Amount

    $100,000

Project Overview

The loss of connections between nerve cells is an early indicator of Alzheimer’s disease. The loss of these connections also causes difficulty thinking and processing information. Unfortunately, we do not yet understand why this connection loss occurs. Research has shown that the structures that make up the connections become unstable…

Project Ongoing

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Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $100,000

Project Overview

Periodontitis, a chronic oral inflammatory disease-causing tissue damage, bone deterioration and tooth loss, has been linked to Alzheimer’s disease. Porphyromonas gingivalis, a key bacterium causing periodontitis, has been found in the brain of Alzheimer’s disease patients, and it is believed to contribute to brain pathology. However, there is a lack…

Project Ongoing

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[99m]Technetium-based radioligands for improving access to state-of-the-art molecular imaging of neurodegeneration

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $100,000

Project Overview

Medical imaging has changed how we study and treat brain degeneration. The best tool for imaging subtle changes to brain proteins is positron emission tomography (or PET). But that has limited availability. An equivalent tool, single-photon emission computed tomography (SPECT) is more available. But SPECT lacks radioactive probes that generate…

Project Ongoing

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Design and Development of Analogues of beta-Alanine as Therapeutics for AD

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Start Date

    2023

  • Total Grant Amount

    $100,000

Project Overview

When brain cells are injured during Alzheimer’s disease, those cells may either die or become too electrically excitable. This study’s objective is to design drugs that prevent harmful levels of electrical excitability in brain cells. The expected outcome of is to discover a prototype new drug for Alzheimer’s disease. This…

Project Ongoing

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User-Centered development and validation of an intelligent drink reminder device

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $100,000

Project Overview

Dehydration can be dangerous for older adults. Complications include urinary tract infections, increased risk of falls, dizziness, weakness, low blood pressure, kidney damage, delirium, and seizures. People living with dementia have a higher risk of dehydration. This study will lead to a solution that reminds people living with dementia to…

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