721 results found
Control of mRNA translation in Microglia response to Alzheimer’s disease pathology
Project Overview
Microglia are the brain’s immune cells, and their role is to protect the brain. Yet in Alzheimer’s disease, these cells are often found diseased as well. In a brain with Alzheimer’s disease, the microglia’s ability to provide instruction is defective. This study’s hypothesis is that restoring translation on microglia will…
Project Ongoing
See the project and researchersAlternative Strategies to Prevent Oral Pathogens Infection and Battle Alzheimer’s Disease
Project Overview
Bacteria involved in gum disease can be found in the brains of people with Alzheimer’s disease and dementia. These bacteria help release toxins into different tissues, including the brain. And these toxins, in turn, increase amyloid beta in the brain, contributing to Alzheimer’s disease. This study will explore how gum-disease…
Project Ongoing
See the project and researchersSensors for rapid detection of Alzheimer’s disease biomarker proteins
Project Overview
Biomarkers are measurable indicators that help determine if a person may have, or be at risk of, developing a disease. Changes in the brain can start more than a decade before first clinical symptoms of Alzheimer’s disease. A simple test to screen for protein biomarkers may help clinicians diagnose Alzheimer’s…
Project Ongoing
See the project and researchersAn intergenerational behavioural intervention to enhance physical activity in older adults at risk for Alzheimer’s disease
Project Overview
Physical activity is one of the most important means of reducing risk of dementia. And new strategies are needed to support older adults in becoming more active. This study will test whether a new cross-generational intervention increases physical activity in adults over 60. The participants are at a high risk…
Project Ongoing
See the project and researchersBring joy and happiness to long-term care by co-building an immersive experience program
Project Overview
People living in long-term care (LTC) homes are often socially isolated. Evidence shows virtual reality (VR) can be used to support the mental health of older adults. Virtual programming supports access to meaningful activities that may help combat boredom and loneliness. People living with dementia may not tolerate traditional VR…