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556 results found

Detection of tandem repeat expansion in neurological disorders

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. It has improved clinical diagnosis and gene discovery for numerous human brain disorders. However, the casual genetic risk factors identified so far generally confer less risk than expected…

Neural predictors of theta burst stimulation

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options. One effective alternative to medication is theta burst stimulation (TBS). This technique uses magnetic fields applied to the outside of the head to modulate brain…

Multi-scale analyses of brain connectivity and dynamics in autism spectrum conditions

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. As ASD remains not very well understood from a neuroscientific perspective, we currently lack diagnostic and intervention approaches that target potential biological mechanisms.…

2019 Dr. Hubert van Tol Travel Fellowship

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Competition

    Dr. Hubert van Tol Travel Fellowship

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $4,165

  • Health Canada Contribution

    $2,082

Project Overview

I was selected to present a poster during one of the 2 poster sessions. The project I presented was aimed at deciphering the molecular function of the Boc receptor in axon guidance. This receptor is necessary for the activation of Shh signaling but how Boc receptor binding to Shh triggers…

Development of a high throughput 3D microphysiologicalplatform for rapid automated assessment of human brain organoids response to drugs targeting neurological disorders

  • Program Type

    Platform grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson'sAlzheimer’s

  • Competition

    CQDM - Brain Canada - Quantum Leap

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $1,600,000

  • Health Canada Contribution

    $800,000

Project Overview

Alzheimer's disease (AD) and Parkinson’s disease (PD) are the most common and devastating neurological diseases, with over 750,000 AD patients and over 100,000 PD patients in Canada. Drug development remains a slow, expensive and inefficient process. The biopharmaceutical industries need alternative models that better predict the human response to drugs…