Directory of funded grants

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556 results found

Nociceptor neurons control cancer immunosurveillance

  • Program Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Azrieli Foundation – Brain Canada Early-Career Capacity Building grants

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Dr. Talbot studies the dialogue between the nervous and immune systems. It is well demonstrated that pain and itch are common features of various cancers, and that cancer cells actively secrete factors promoting neuronal infiltration of tumors. Recent data suggests that experimentally stopping the electrical signals of tumor infiltrating neurons…

Project Complete

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Mapping the cellular origins of circuit vulnerability in neurodevelopmental disorders

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Autism

  • Competition

    Azrieli Foundation – Brain Canada Early-Career Capacity Building grants

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The brain is an incredibly complex organ. Much of the brain's complexity may be attributed to the circuitry that resides within. Synaptic connections are the key units of information transduction and therefore and therefore an increasing amount of research focus has centered on understanding how they normally function and how…

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Decoding the RNA stability programs that determine cell identity and function in human brain and neurodegenerative disorders

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Azrieli Foundation – Brain Canada Early-Career Capacity Building grants

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The brain cells in Alzheimer’s disease patients differ extensively from healthy brain cells at the molecular level: there are hundreds of genes that are normally active in the brain, but become inactive in Alzheimer’s. Similarly, Alzheimer’s disease appears to turn on hundreds of genes that are normally inactive in the…

Project Complete

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The role of cortical inhibitory cells in human epilepsy

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Epilepsy

  • Competition

    Azrieli Foundation – Brain Canada Early-Career Capacity Building grants

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Epilepsy is a debilitating neurological disorder that affects up to one percent of the world’s population. A third of epileptic patients suffer from drug-resistant form of the disease for which brain surgical intervention is often necessary. The current scientific challenge is twofold: first to advance our understanding of the biological…

Project Ongoing

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Detection of misfolded TDP-43 in CSF of ALS cases: Diagnostic potential of confirmation-specific antibodies

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Canada – Brain Canada Trainee Program 2018

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $165,000

  • Health Canada Contribution

    $82,500

Project Overview

A more streamlined way to diagnose ALS earlier is desperately needed as current methods can take up to two years and rely heavily on ruling out other conditions that share similar symptoms. One of the hallmarks of ALS for 97 per cent of cases is the accumulation of misfolded TDP-43…

Project Ongoing

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