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Reversing Cardiac Chaos: Cardiac Benefits of Epidural Electrical Stimulation (EES) in Acute Spinal Cord Injury Mice

  • Grant Type

    Capacity building grants

  • Competition

    Rising Stars Trainee Awards

  • Province

    Alberta

  • Start Date

    2024

  • Total Grant Amount

    $5,000

Project Overview

Background: A spinal cord injury (SCI) disrupts communication between supraspinal cardiovascular control centers and the regions of the spinal cord that regulate cardiac function. The consequence is a dysregulation of the cardiovascular system and a three-fold increased risk of heart disease. We recently demonstrated that epidural electrical stimulation (EES) targeting…

Project Ongoing

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Investigating the interaction between cell adhesion molecule 2 (CADM2) genetic variation and cannabinoids using behavioural and neurochemical assessments

  • Grant Type

    Capacity building grants

  • Competition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $3,026

Project Overview

CADM2 is a gene located on chromosome 3. This gene is primary expressed in the brain, especially in regions that are known to be involved in substance-use related behaviours, cognition, and impulsivity. Previous research has shown that variations in the CADM2 gene are connected to different attentional and impulsivity traits.…

Project Ongoing

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Ultrasound-assisted modulation of endothelial immunobiology in the context of CARNK-92 cell chemotaxis for cellular immunotherapy

  • Grant Type

    Capacity building grants

  • Competition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Start Date

    2024

  • Total Grant Amount

    $5,000

Project Overview

Cellular immunotherapy has met initial exciting success against blood-borne cancers yet remains severely hindered in the context of solid tumors, including glioblastoma. One of the main reasons for this is the immune-suppressive tumor microenvironment, in which key adhesion molecules are downregulated to hinder immune cell trafficking, and the secretion of…

Project Ongoing

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Multimodal precision neuroimaging of the individual human brain at ultra-high field

  • Grant Type

    Capacity building grants

  • Competition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Start Date

    2024

  • Total Grant Amount

    $4,975

Project Overview

Multimodal neuroimaging allows for a non-invasive examination of the structure and function of the human brain. The traditional way of analyzing data has for a long time been to acquire short, standard sessions and to average data across individuals, which limits the specificity of findings and may in some cases…

Project Ongoing

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The impact of TREM2 polymorphism on microglial function in Alzheimer’s Disease pathogenesis

  • Grant Type

    Capacity building grants

  • Competition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $3,500

Project Overview

Genetic variation in the TREM2 protein is associated with an increased risk of developing Alzheimer’s disease. TREM2, expressed on the surface of brain immune cells (microglia), helps microglia activate, clear harmful proteins like amyloid beta (Aβ), and prevent their buildup—key processes in protecting against AD. However, a variant near the…

Project Ongoing

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