Directory of funded grants

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586 results found

Dysregulation of integrated stress response (ISR) pathway in Fragile X syndrome and autism

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

Mr. Hooshmandi's research will examine the hypothesis that reduced phosphorylation of eIF2α excessively stimulates general translation in Fmr1 KO mice during brain development, contributing to the pathophysiology of Fragile X syndrome (FXS) and potentially of other forms of autism. They propose three main aims in this study as follows: (1)…

Sex differences in exercise efficacy: Possible role of BDNF and stress axis

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association Research Fellowship

  • Province

    British Columbia

  • Start Date

    2018

  • Total Grant Amount

    $227,500

  • Health Canada Contribution

    $113,750

Project Overview

Research suggests that exercise can help improve brain health and decrease the risk of dementia, but there is variation in the benefit of different exercise interventions. Cindy Barha, Ph.D. and colleagues hypothesize that male and female brains may respond in different ways to different types of exercise such as aerobic…

Translating research into practice: Investigating the impact of Alzheimer’s disease diagnostics in Canada

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Improving Health Outcomes and Quality of Life

  • Province

    British Columbia

  • Start Date

    2018

  • Total Grant Amount

    $684,000

  • Health Canada Contribution

    $342,000

Project Overview

Alzheimer’s disease causes progressive neurological decline and substantially decreases the quality of life of the individuals with the disease and their caregivers. Today, there are over half a million Canadians living with Alzheimer’s disease or a related form of dementia, directly costing Canada $10.4 billion a year. With a rapidly…

Stroke Recovery in Motion

  • Grant Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Improving Health Outcomes and Quality of Life

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $1,000,266

  • Health Canada Contribution

    $500,133

Project Overview

One in six people worldwide will experience a stroke in their lifetime. One third of these people are left permanently disabled. In 2013, at least 405,000 Canadians were living with long-term stroke disability and this number is projected to increase to 726,000 over the next 20 years. Advances in acute…

Toward exercise as medicine for adolescents with bipolar disorder

  • Grant Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Improving Health Outcomes and Quality of Life

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $458,000

  • Health Canada Contribution

    $229,000

Project Overview

This project focuses on improving aerobic fitness (AF) among adolescents with bipolar disorder (BD). BD affects 2-5% of adolescents and is the 4th most disabling medical condition among adolescents worldwide. Even with treatment, adolescents with BD spend over half of the time with mood symptoms that impair quality of life.…