Directory of funded grants

Filter by

661 results found

Physical fingerprints of single extracellular vesicles for liquid biopsy in brain cancer

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $150,000

  • Health Canada Contribution

    $75,000

Project Overview

Need for project: Glioblastoma (GBM) is an incurable brain cancer that changes rapidly confounding standard diagnostic and therapeutic methods. These changes in molecular composition can be captured by bits of cancer cells known as extracellular vesicles (EVs) found in blood of patients (liquid biopsy), but it is very difficult to…

Project Ongoing

See the project and researchers

Radiomics and machine learning based non-invasive biomarkers for prediction of peritumoral invasion in brain metastases

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $150,000

  • Health Canada Contribution

    $75,000

Project Overview

Need for project: Treatment of brain metastases (BrM) includes a combination of surgery and radiation therapy (RT). Recurrence after treatment is a problem that limits survival and quality of life. Our team has discovered that highly invasive growth of BrM is associated with recurrence and sensitivity to particular systemic treatments.…

Project Ongoing

See the project and researchers

Precision diagnosis and prognosis of primary and metastatic brain tumours using DNA methylation profiling in liquid biopsy

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $149,760

  • Health Canada Contribution

    $74,880

Project Overview

Need for project: More sensitive molecular tools are needed in the field of neuro-oncology to enable early detection, more accurate diagnosis, and prediction of outcome for brain tumors. We have early experience in establishing that DNA methylome signatures in liquid biopsy can be used as a highly sensitive approach for…

Project Complete

See the project and researchers

Early diagnosis of gliomas by using a novel multiplexed serum proteomic technology

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Québec

  • Start Date

    2021

  • Total Grant Amount

    $150,000

  • Health Canada Contribution

    $75,000

Project Overview

Need for project: Gliomas are among the most malignant tumors, with very poor survival rates. Early diagnosis is highly desirable since it can facilitate more effective treatments of small tumors, which have not as yet extensively metastasized. It is thus of upmost importance to find non-invasive biomarkers of early glioma…

Project Ongoing

See the project and researchers

Safety and feasibility of focused ultrasound-enabled liquid biopsy in patients with brain tumours

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CCS/CIHR/BC Spark Grant: Novel Technology Applications in Cancer Prevention and Early Detection

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $150,000

  • Health Canada Contribution

    $75,000

Project Overview

Need for project: Neuropathological diagnoses of brain tumours require invasive neurosurgical biopsies that carry a risk of morbidity or mortalityto patients. There has been growing interest in the use of non-invasive liquid biopsies to sample cell-free circulating tumorDNA (ctDNA) for genomic and epigenomic analyses but the abundance of ctDNA in…

Project Ongoing

See the project and researchers