Directory of funded grants

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586 results found

Enhancing the efficacy of heat shock protein inducers by cotreatment with a histone deacetylase inhibitor – A therapeutic strategy for ALS

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Arthur J. Hudson Translational Team Grant

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $1,727,424

  • Health Canada Contribution

    $863,712

Project Overview

In ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins can become misfolded and clump together, potentially damaging nerve cells. When a healthy body responds to stress, protective mechanisms increase the production of heat shock proteins that help prevent protein misfolding. This mechanism can become…

Project Ongoing

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Validation of ocular measures as potential biomarkers for early detection of brain amyloid and neurodegeneration

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    The W. Garfield Weston Foundation

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $509,747

  • Health Canada Contribution

    $254,874

Project Overview

500,000 Canadians have dementia, a number that will double within a generation due to the ongoing aging demographics of the population, with annual costs estimated to increase from $15B currently to over $150B by the year 2050. The estimated total cost to the society including the loss of productivity by…

Project Complete

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Neuronal mechanisms of human episodic memory

  • Grant Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    BRAIN Initiative

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $1,033,182

  • Health Canada Contribution

    $516,591

Project Overview

The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. The objective of this project is to assemble a multi-disciplinary and multi-site team with the expertise and patient volume to test key…

Project Complete

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Early Years Intervention on a First Nations Reserve

  • Grant Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Early Years Initiative

  • Province

    Alberta

  • Start Date

    2018

  • Total Grant Amount

    $3,461,100

  • Health Canada Contribution

    $1,730,550

Project Overview

Recognizing that the 9 months before birth and the early years of a child’s life are the most critical period in the shaping of the structures and functions of the brain, and the importance of high quality, culturally appropriate early childhood programming for Indigenous children and families prior to kindergarten…

Project Ongoing

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Canadian Open Neuroscience Platform (CONP)

  • Grant Type

    Platform grants

  • Area of research

    Neurotechnology

  • Disease Area

    Other

  • Competition

    Open Neuroscience/Data Sharing PSG

  • Province

    Québec

  • Start Date

    2017

  • Total Grant Amount

    $10,207,130

  • Health Canada Contribution

    $5,103,565

Project Overview

The Canadian Open Neuroscience Platform (CONP) is a national platform for open sharing of neuroscience research data and brings together many of the country’s leading scientists in basic and clinical neuroscience to form an interactive network of collaborations in brain research, interdisciplinary partnership, clinical translation and Open Publishing. The goal…

Project Complete

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