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552 results found

Habitual physical activity, exercise and cardiovascular function in spinal cord injury

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    Heart and Stroke Foundation Emerging Research Leaders Initiative

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $149,282

  • Health Canada Contribution

    $74,640

Project Overview

The major objectives of this research program are to measure the function of the heart and blood vessels following SCI and to investigate the mechanisms that are responsible for any changes that occur. A second objective is to examine the effect that both physical activity, which describes any bodily movement,…

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Genomic markers of cerebral small vessel ischemia

  • Program Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Heart and Stroke Foundation Emerging Research Leaders Initiative

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $148,260

  • Health Canada Contribution

    $74,130

Project Overview

The overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain. Specifically we will investigate patients that have had strokes or dementia due to small vessel disease, or who have brain imaging showing evidence of damage to the small blood vessels…

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Neuroinflammatory susceptibility to vascular disease as a dementia driver

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $194,981

  • Health Canada Contribution

    $97,490

Project Overview

Recent studies have shown that damage to the small blood vessels in the brain (cerebrovascular disease) may increase the risk for Alzheimer’s. However, not everyone with small vessel damage develops memory problems, suggesting there are other factors that mediate this risk. Since brain inflammation is a key characteristic of both…

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Sleep, cognition, and inflammation following natural or surgical menopause

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association Research Fellowship

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $181,295

  • Health Canada Contribution

    $90,648

Project Overview

Alzheimer’s disease disproportionately affects women and emerging evidence suggests there may be unique biological and lifestyle factors that underlie these differences. A woman’s brain health, for example, may be affected more strongly than a man’s by the presence of APOE-e4, a gene variant linked to Alzheimer’s risk. Nicole Gervais, Ph.D.,…

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Preventing Language Decline in Dementia 

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $109,068

  • Health Canada Contribution

    $54,534

Project Overview

Primary progressive aphasia (PPA) is a form of dementia which impairs the ability to understand spoken and written language but other cognitive skills (including memory) remain intact for several years after its onset. Ideally, interventions to improve communication abilities in people with PPA would begin during the earliest stages when…

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