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Funded Grants

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Dysregulation of integrated stress response (ISR) pathway in Fragile X syndrome and autism

Project Overview

This project is focused on role of the integrated stress response (ISR) pathway in fragile X syndrome as well as autism.  Mehdi Hooshmandi is aiming to figure out the exact ISR pathway abnormalities in different cell types and regions of the brain. Once the altered molecule(s) is identified, it will be possible to manipulate the pathway pharmacologically. Moreover, this may lead to a potential biomarker for early diagnosis of neurodevelopmental diseases including fragile X syndrome and autism.

Principal Investigator

Mehdi Hooshmandi , McGill University

Partners and Donors

McGill University

Project Ongoing

Dysregulation of integrated stress response (ISR) pathway in Fragile X syndrome and autism

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Contact Us

1200 McGill College Avenue
Suite 1600, Montreal, Quebec
H3B 4G7

+1 (514) 989-2989 info@braincanada.ca

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