Brain Canada Brain Canada
FR Donate

Identification of Brain Metastasis Initiating Cells and Regulators of Brain Metastasis from Lung Cancer

Principal Investigator:
  • Mohini Singh, McMaster University

Project Overview

Ms. Singh’s project investigates brain metastases (BMs) – the most frequent type of brain tumour to occur in adults. The specific goals of her project include functional characterization of BMIC regulatory genes using a new human-mouse BMIC xenograft model, predictive signatures for patients with lung cancer, and to assess the clinical utility of the genes identified as regulators of BM and/or a putative BMIC population.