Brain Canada Brain Canada
FR Donate

Immunotherapy as a targeted low-impact treatment of paediatric brain cancers

Principal Investigator:
  • Laura Donovan, The Hospital For Sick Children
  • Hospital for Sick Children

Project Overview

Laura Donovan is investigating the use of Chimeric Antigen Receptor (CAR)-armed T cell based therapy as a potent and specific immunotherapy against paediatric medulloblastoma and ependymoma, by utilizing elegant in vivo and in vitro multimodal systems. Her research could significantly influence the design of the next generation of clinical trials for children with brain tumours.