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Funded Grants

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Investigating altered functional brain networks in autism spectrum disorder

Project Overview

Autism Spectrum Disorder (ASD) is a complex developmental brain disorder characterised by impaired communication and repetitive behaviors, and is often accompanied by intellectual disability. According to the Public Health Agency of Canada, 1 in 66 children and youth in Canada is diagnosed with ASD. The personal and societal costs of treatment and caregiving are immense with lifetime financial costs of $1.2-4.7 million to care for “typical” individuals with ASD. Current therapeutic interventions for ASD are oriented toward symptom management but there is no treatment for the underlying disorder, as the cause of the disorder remains unknown. A greater understanding of the basis of ASD is imperative to develop the most effective diagnostic criteria and treatments. Neuroimaging studies have indicated that brain network dysfunction is an important feature of ASD. This proposal aims to investigate brain dysfunction associated with ASD in novel ways, using light-based methods for imaging and manipulating brain activity in animal models. These innovative techniques incorporate a scale of assessment, called mesoscale, which allows the assessment of brain activity at both a microscopic level and a brain-wide level at the same time. By furthering the understanding of the neuroimaging features of ASD, as well as how altered brain activity manifests in the symptoms of ASD, this research will inform the development of diagnostic criteria and treatments for ASD.

Principal Investigator

Allen Chan , University of Alberta

Partners and Donors

The Azrieli Foundation

Project Ongoing

Investigating altered functional brain networks in autism spectrum disorder

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Contact Us

1200 McGill College Avenue
Suite 1600, Montreal, Quebec
H3B 4G7

The offices of Brain Canada Foundation are located on the traditional, ancestral territory of the Kanien'kehá:ka Peoples, a place which has long served as a site of meeting and exchange amongst nations.

+1 (514) 989-2989 info@braincanada.ca

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