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Neurophysiological basis of amblyopia and its treatment

Project Overview

Amblyopia (commonly known as “lazy eye”) is a common developmental visual disorder, caused by eye misalignment, unequal refractive error between two eyes, or visual deprivation, with lifelong consequences on learning and academic achievements that we do not fully understand. It affects 4.7% of Canadian children, and 22-41% of children do not respond to conventional treatment. The proposed study aims to improve our understanding and treatment of amblyopia by looking at aspects of vision that are known to be disrupted by amblyopia but are not currently part of the clinical definition. Behavioural and neuroimaging measures will be used with children and adolescents. The goal is to identify the neurophysiological mechanisms underlying treatment outcomes, which in future will allow clinicians to recommend specific treatment strategies depending on the deficits with which a child presents.

Principal Investigator

Arijit Chakraborty , BC Children’s Hospital Research Institute (BCCHR)

Partners and Donors

BC Children's Hospital Research Institute - University of British Columbia

Project Ongoing

Neurophysiological basis of amblyopia and its treatment

  • Program Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    British Columbia

  • Start Date

    2018

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000