Directory of funded grants

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556 results found

A national coordinating neuroinformatics framework for autism and related conditions

  • Program Type

    Team grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Québec

  • Start Date

    2016

  • Total Grant Amount

    $1,552,398

  • Health Canada Contribution

    $776,199

Project Overview

New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development. Such approaches dwarf the resources of most laboratories, who are increasingly moving toward…

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Novel approaches to early detection and treatment of ASD

  • Program Type

    Team grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Alberta

  • Start Date

    2016

  • Total Grant Amount

    $2,086,742

  • Health Canada Contribution

    $1,043,371

Project Overview

More than 1 in 100 individuals are diagnosed with Autism Spectrum Disorder (ASD), with profound impacts on the quality of life of those who are affected and their families. Until recently, children were rarely referred for assessment before age 2, so we knew little about ASD early in life. Prior…

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Testing therapeutic approaches to improve cognitive dysfunction in a primate model of Alzheimer’s Disease

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    2015 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $857,062

  • Health Canada Contribution

    $428,531

Project Overview

Alzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called amyloid-beta oligomers (AβOs). The pursuit of new disease-modifying therapeutics for AD that change the natural progression of AD early in its course is under intense investigation. A major…

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Novel approaches to understand the role of cAMP and co-signaling cascades in synaptic plasticity and brain disorders

  • Program Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    2015 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $1,850,000

  • Health Canada Contribution

    $925,000

Project Overview

Synaptic plasticity is the process where the strength of connections between nerve cells is altered by experience. It is widely believed that synaptic plasticity is used to store information in the brain and is important for learning and memory and other major cognitive processes. The most widely studied form of…

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Cognitive Outcomes and Response/Remission Efficacy of Convulsive Therapies in Treatment Resistant Depression: The CORRECT-TRD Trial

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    2015 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $1,387,424

  • Health Canada Contribution

    $693,712

Project Overview

Magnetic Seizure Therapy (MST) is a novel form of treatment that uses high intensity magnetic field pulses to stimulate the brain and induce a seizure as a therapeutic intervention for patients with depression resistant to antidepressant medication, known as Treatment Resistant Depression (TRD). Preliminary research has shown that MST is…

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