Directory of funded grants

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551 results found

Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric Disorders

  • Program Type

    Team grants

  • Area of research

    Multiple

  • Disease Area

    AutismMental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $1,387,500

  • Health Canada Contribution

    $693,750

Project Overview

Autism spectrum disorders are neurodevelopmental disorders characterized by deficits in social interaction, poor communication, and restricted, stereotyped patterns of behavior. Autism and schizophrenia affect over 1% of the population, and each has strong genetic associations with 60-90% heritability among twins. Recent research identified mutations in a shared genetic pathway in…

The Frontier Trial – Field Randomization of NA-1 Treatment In Early Responders

  • Program Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    2014 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2016

  • Total Grant Amount

    $8,068,664

  • Health Canada Contribution

    $3,956,135

Project Overview

Stroke is a life threatening emergency caused by blocked arteries that affects 45,000 Canadians a year. Each hour a stroke is left untreated means brain cells are dying. The only emergency treatment we have is a clot busting agent that can re-open blocked arteries if given within 3-4.5 hours of…

Understanding stress to improve mental health

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    Alberta

  • Start Date

    2015

  • Total Grant Amount

    $1,387,500

  • Health Canada Contribution

    $693,750

Project Overview

Recent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses. These issues are exacerbated by stress. This is important because an acute episode of stress is the most common trigger for breakthrough presentations of many mental illnesses, and when stress-related disorders are…

Prevention of Alzheimer’s Dementia in High Risk Populations: A Randomized Controlled Trial of a Combination of Cognitive Remediation and Brain Stimulation

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Chagnon Family and Brain Canada Interventions for Prevention of Alzheimer Disease and Related Disorders (ADRD) MIRI

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $11,196,085

  • Health Canada Contribution

    $4,998,044

Project Overview

This project is studying a novel intervention in 250 older persons whose major depression has been successfully treated with an antidepressant medication: a combination of cognitive remediation (CR, consisting of memory and problem solving exercises) plus transcranial Direct Current Stimulation (tDCS, a non-painful low electrical current that circulates through the…

Structural and functional networks in Autism Spectrum Disorder and Fragile X Syndrome

  • Program Type

    Team grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Québec

  • Start Date

    2014

  • Total Grant Amount

    $2,492,735

  • Health Canada Contribution

    $1,246,368

Project Overview

Many childhood disorders, such as Autism Spectrum Disorder (ASD) or Fragile X Syndrome (FXS), are a result of abnormal growth and connections throughout the brain, rather than being caused by some specific pathology, such as a tumour. For meaningful diagnosis, prognosis and intervention for these devastating disorders to be able…