Directory of funded grants

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551 results found

Epigenetics and mental health: the Canadian neuroepigenetics network

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    W. Garfield Weston Foundation – Brain Canada Multi-Investigator Research Initiative (MIRI)

  • Province

    Québec

  • Start Date

    2013

  • Total Grant Amount

    $1,494,900

  • Health Canada Contribution

    $747,450

Project Overview

Psychiatry, like all areas of medicine and biology, has long considered the origins of individual differences. This issue ultimately produced a nature vs nurture schism that divided researchers who emphasized the importance of environmental influences from those who considered the importance of heritable variation in the genome. This was never…

Dissecting acetylcholine/glutamate co-transmission in the striatum: importance of individual neurotransmitter in addiction and movement disorders

  • Program Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    2012 MIRI Team Grants

  • Province

    Québec

  • Start Date

    2014

  • Total Grant Amount

    $1,424,634

  • Health Canada Contribution

    $712,317

Project Overview

Parkinson’s disease and addiction have tremendous human and economical costs for our society. The secret to understand these pathologies lies in unravelling the functioning of a specific brain region named striatum. The striatum regulates several behavioural outputs that are affected in Parkinson’s disease and addiction, including motor control, learning of…

Propagated protein misfolding of SOD1 in ALS: Exemplar for neurodegeneration

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    2012 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2014

  • Total Grant Amount

    $1,425,000

  • Health Canada Contribution

    $712,500

Project Overview

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive fatal disease that affects the nerve cells responsible for muscle movement (motor neurons). The disease is characterized by systematic paralysis of the muscles of the limbs, speech, swallowing, and respiration, due to the progressive death of motor…

Non-invasive treatment of pediatric neurological disorders using MR-guided focused ultrasound (MRgFUS)

  • Program Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    StrokeEpilepsy

  • Competition

    2012 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $1,329,420

  • Health Canada Contribution

    $664,710

Project Overview

Neuroscientists and engineers at the University of Toronto, Hospital for Sick Children, and University Health Network and Thunder Bay Regional Research Institute have joined together to develop a novel next generation non-invasive treatment technique, MR guided Focused Ultrasound (MRgFUS), for two common and disabling pediatric neurological conditions, stroke and drug…

Carrier-mediated delivery of therapeutic proteins into the brain

  • Program Type

    Team grants

  • Area of research

    Neurotechnology

  • Disease Area

    Other

  • Competition

    2012 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $1,662,500

  • Health Canada Contribution

    $831,250

Project Overview

It is estimated that diseases of the brain currently affect over 1.5 billion people worldwide and account for approximately a third of global disease burden. For many neurological diseases, such as Parkinson's disease, Huntington's disease, autism and epilepsy, the available treatments are focused on symptom relief, rather than a cure.…