720 results found
DNA methylation signatures in a rat model of Fetal Alcohol Spectrum Disorder
Project Overview
Prenatal alcohol exposure can result in abnormal brain development, causing Fetal Alcohol Spectrum Disorder (FASD), which is linked to a number of cognitive, behavioural, and immune deficits that last across the lifetime. Although the lasting effects of alcohol on development are well studied, the molecular changes causing these deficits remain…
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See the project and researchersCombined Analysis of Brain Magnetic Resonance Images Towards Patient Specific Diagnosis of Fetal Alcohol Spectrum Disorder
Project Overview
Mr. Little’s current focus is on building computer software that can identify altered brain development patterns in fetal alcohol spectrum disorder (FASD) using brain images. The aim is to create an objective tool that can detect atypical brain development and potentially monitor the effects of interventions. His goal is to…
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See the project and researchersDoes rehabilitation improve brain structure/function and motor outcomes of children with developmental coordination disorder?
Project Overview
Ms. Izadi-Najafabadi’s research focuses on the effect of Cognitive Orientation to Occupational Performance (CO-OP)—the current best-practiced intervention for children with Developmental Coordination Disorder (DCD)—on their structural and functional brain connectivity. This study also explores how children with dual diagnosis of Attention Deficit Hyperactive Disorder (ADHD) and DCD will respond to…
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See the project and researchersPrenatal serotonin reuptake inhibitor (SRI) antidepressant exposure on brain development, cognition and activity related risk for obesity: A longitudinal study with 10 year olds
Project Overview
Dr. Hutchison‘s training is in lifespan psychology and her research broadly focuses on children’s cognitive and social development. her current research project examines cognitive and health outcomes in children whose mothers’ were treated with antidepressant medication during pregnancy. About 10- 20% of women experience depressed mood during pregnancy and Serotonin…
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See the project and researchersImmunotherapy as a targeted low-impact treatment of paediatric brain cancers
Project Overview
The existing treatment regimens for children with ependymomas are generally not successful and if successful survivors are left with considerable disabilities including severely diminished IQ, focal neurological and language deficits, and endocrine deficiencies. Dr. Donovan's current proposal aims to develop an improved targeted therapy, which will increase survival rates, and…