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827 results found

Epitranscriptomic regulation of sleep, neurodegeneration, and longevity

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

Project Overview

This research proposal investigates how a chemical modification called N6-methyladenosine (m6A) on messenger RNA influences brain health, specifically focusing on its role in sleep regulation, learning and memory, and neurodegenerative diseases such as Alzheimer's. m6A is an RNA modification that affects gene expression and protein production, and it has been…

Project Ongoing

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Trajectoires cérébrales normatives et atypiques : repenser le suivi du neurodéveloppement pédiatrique

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Brain Injury

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Les commotions cérébrales chez les enfants sont un problème de santé publique majeur en raison de leur impact à long terme sur le développement cognitif et socio-émotionnel. La période de 0 à 5 ans est cruciale pour le développement cérébral, mais peu d'études se sont penchées sur la variabilité individuelle…

Project Ongoing

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Phenotyping of Alzheimer’s disease across imaging-defined stages of cerebral amyloid angiopathy

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Background: Mixed dementia is the most common form of dementia. It occurs when Alzheimer’s disease (AD) combines with vascular disease, affecting both the blood vessels and the immune function in our brain. As this happens, memory difficulties develop. However, typical AD research has neglected the blood vessel health and associated…

Project Ongoing

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Understanding cerebral blood flow control in humans after cannabis use

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood. While cannabis containing the psychoactive compound Δ-9-tetrahydrocannabinol (THC) is widely consumed, research suggests that THC may significantly alter the regulation of brain blood flow. Proper blood flow to…

Project Ongoing

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Identifying Proteogenomic Signatures Of Smoldering Lesions in Multiple Sclerosis

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Multiple sclerosis (MS) is the most common cause of non-traumatic neurological disability, affecting 1 in 400 Canadian adults. It occurs when the immune system mistakenly attacks the brain and spinal cord, causing nerve damage. While current treatments reduce relapses, many patients still experience worsening disability over time. This progression is…

Project Ongoing

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