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617 results found

Towards inclusive genetic and protein biomarkers for improved multiple sclerosis risk stratification and etiology

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2024

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Canada has one of the world’s highest rates of multiple sclerosis (MS), a disease that can lead to significant disability. There is growing evidence that MS might be preventable, presenting an exciting opportunity. However, achieving this goal requires that we better understand the causes of MS and develop biomarkers that…

A physiologic-to-tissue level approach to characterize the pathophysiology of hypoxic ischemic brain injury in humans.

  • Grant Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    British Columbia

  • Start Date

    2024

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

During a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. This lack of blood flow and oxygen leads to a severe brain injury called a hypoxic-ischemic brain injury. Even if the heart starts beating again following cardiopulmonary resuscitation, patients…

Human choroid plexus organoids to investigate unexplored mechanisms and secreted biomarkers in neurodevelopmental disease

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Epilepsy

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    British Columbia

  • Start Date

    2024

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Our brains are built by neural stem cells (NSCs), which produce all the neurons and other specialized cells that form the brain and execute its functions. We understand many of the internal processes NSCs use to control which cells they will produce and when. However, we also know the environment…

Polygenic applications of aging to brain and cognitive reserve in multiple sclerosis

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Manitoba

  • Start Date

    2024

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Reserve is someone's ability to tolerate age-related changes and disease-related insults to their brain without developing symptoms. How reserve contributes specifically to multiple sclerosis disease is unknown. There are two types of reserve: "Brain reserve" which is like an individual's "hardware", and "cognitive reserve" which is your "software". Whether differences…

Dissecting brain-wide functional circuits underlying social decision making by developing a naturalistic virtual reality platform of juvenile zebrafish

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Understanding how the brain works when we make decisions during social interactions has been difficult for neuroscientists. This is because our brains process multiple things all at once all the time, and different regions of the brain need to communicate with each other to process information. Previous studies have found…