768 results found
Does the Epstein-Barr virus activate immune cells before multiple sclerosis becomes symptomatic?
Project Overview
Multiple Sclerosis (MS) is a serious chronic neurological condition, particularly common among young adults in Canada. The exact cause of MS is unknown, but it involves immune cells mistakenly attacking the brain and spinal cord. Symptoms often worsen over time and become chronic, leading to eyesight, movement, mood, and/or memory…
Project Ongoing
See the project and researchersDevelopment of Genetic Screening Platforms for Immune Evasion in Glioblastoma
Project Overview
In 2023, over 3,000 Canadians were newly diagnosed as brain tumor, and around 2,500 succumbed to this disease. Despite strenuous efforts to fight against this serious illness, brain tumor is still hard to be cured, and more than half of the patients die within five years of diagnosis. Brain is…
Project Ongoing
See the project and researchersInterrogating the role of glial development in models of attention deficit hyperactivity disorder
Project Overview
Attention-deficit hyperactivity disorder (ADHD) is the most common disorder that impacts development of the brain. ADHD is characterized by hyperactivity and inattention in children; the consequences of which can lead to more frequent need for health care and loss of productivity as an adult. While drugs exist to treat ADHD,…
Project Ongoing
See the project and researchersSexual Development and Inflammatory Bowel Disease: The Microbiome- Hormone-Brain Axis
Project Overview
The microbes living in our gut have recently been found to affect important developmental processes such as brain development and hormonal regulation during puberty. Microbes produce compounds that affect the brain, as well as change the activity of sex hormones. Despite these recent advances, there remains a wide knowledge gap…
Project Ongoing
See the project and researchersElucidating the microvascular origin and behavioral correlates of functional connectivity during aging
Project Overview
The emerging consensus that the brain functions as a single, complex system has led to the popularity of a network approach to studying brain function. Functional connectivity, a measure of the coordinated activity between brain regions, has been observed in neuroimaging studies to change during aging and could be related…