Directory of funded grants

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587 results found

Interleukin-1 blockade along with hypothermia to prevent cerebral palsy arising from refractory neonatal asphyxia

  • Grant Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

Neonatal asphyxia and subsequent cerebral palsy (CP) is a severe pathology resulting from lack of oxygen and/or infection-inflammation. This disease still leads to mortality or severe brain injuries and long-term disabilities. Therapeutic hypothermia (decreased body temperature to 33-34°C during 3 days) is the only treatment available for these newborns. Despite…

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Novel approaches to central nervous system white matter repair

  • Grant Type

    Team grants

  • Competition

    Brain Repair Program

  • Province

    Ontario

  • Start Date

    2004

  • Total Grant Amount

    $1,500,000

Project Overview

Many nerve cells in the body are covered with a protective sheath known as myelin, which allows fast conduction of nerve impulses, and which is produced by two different types of cells called oligodendrocytes and Schwann cells. Demyelination occurs when this protective covering is destroyed, resulting in impaired nerve function.…

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Transforming research on chronic pain

  • Grant Type

    Team grants

  • Competition

    Brain Repair Program

  • Province

    Ontario

  • Start Date

    2004

  • Total Grant Amount

    $1,500,000

Project Overview

Pain affects millions of people worldwide and has a profound negative effect on quality of life. Untreated pain is the most common cause of disability that impairs life. Acute pain is a normal sensation triggered by the nervous system to alert the body to an injury. Chronic pain, on the…

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Mitochondrial dysfunction and neuronal demise: Insights provided by Parkinson’s disease genes

  • Grant Type

    Team grants

  • Competition

    Brain Repair Program

  • Province

    Québec

  • Start Date

    2007

  • Total Grant Amount

    $1,500,000

Project Overview

Converging research efforts have recently identified five genes that are associated with familial Parkinson’s Disease (PD), a condition associated with severe motor dysfunction and loss of dopamine-producing cells in the brain. These genes include α-synuclein, Parkin, DJ-1, Pink1, LRRK2. It is striking that all of them have been linked directly…

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Novel therapeutic strategies to repair brain abnormalities in psychiatric disorders

  • Grant Type

    Team grants

  • Competition

    Brain Repair Program

  • Province

    British Columbia

  • Start Date

    2007

  • Total Grant Amount

    $1,500,000

Project Overview

Communication between brain cells is essential for normal brain function. Healthy brain cells are controlled through chemical messengers that stimulate or inhibit brain activity. Current theories indicate that psychiatric disorders such as addiction, schizophrenia, autism and mental retardation evolve from an imbalance of these chemical messengers leading to a disruption…

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