Directory of funded grants

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590 results found

Investigating Blood Brain Barrier Permeability in an Experimental Model of Juvenile Stroke Using Advanced MR Imaging

  • Grant Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $110,000

  • Health Canada Contribution

    $55,000

Project Overview

Stroke is one of the leading causes of cerebral palsy in children that carried to term, and 60% have lifelong consequences.  Currently, treatment of childhood stroke is limited to prevention of more strokes.  Dr. Domi’s research uses specialized imaging techniques to study the role of the blood-brain barrier, a mechanism…

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The Effects of Glucocorticoids on the Developing Brain

  • Grant Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

The hippocampus has the highest concentration of glucocorticoid receptors in the brain, and is therefore a primary target for glucocorticoids. The fetus may be exposed to increased levels of glucocorticoids as a result of maternal stress/anxiety, or by maternal treatment with synthetic glucocorticoids (sGC); ~10% of all pregnant women are…

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Maternal care and child neurodevelopment: A longitudinal gene x environment analysis of socio-emotional development with an integrated approach

  • Grant Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2016

  • Total Grant Amount

    $60,000

  • Health Canada Contribution

    $30,000

Project Overview

Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. However, the impact varies across the population, as some individuals are resilient. Their genetic architecture may hold the secrets to the differential susceptibility. Mr. Chen’s research looks at how genomic risk profile for…

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Development of novel oligonucleotide delivery modalities for Huntington disease

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Other

  • Competition

    Brain Canada-Huntington Society of Canada Creating HD Clinician-Scientist-to-Patient Virtual Networks Multi-Investigator Research Initiative (MIRI)

  • Province

    British Columbia

  • Start Date

    2017

  • Total Grant Amount

    $950,000

  • Health Canada Contribution

    $475,000

Project Overview

Huntington disease (HD) is an inherited neurodegenerative disease that affects approximately 1 in 7500 individuals in the Western world. The cause of HD is a mutation in one copy of the HTT gene, which produces the toxic mutant huntingtin protein responsible for the brain cell loss associated with the disease.…

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Gangliosides in Huntington’s disease: from bench to clinics and back

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Other

  • Competition

    Brain Canada-Huntington Society of Canada Creating HD Clinician-Scientist-to-Patient Virtual Networks Multi-Investigator Research Initiative (MIRI)

  • Province

    Alberta

  • Start Date

    2016

  • Total Grant Amount

    $950,000

  • Health Canada Contribution

    $475,000

Project Overview

Huntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the brain that control movement, reasoning and emotions. HD patients also suffer from depression and personality changes.  There is no cure for HD. Symptoms progress steadily until patients can no longer conduct a normal…

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